男性乳腺浸润性乳头状癌在细针穿刺抽吸活检时被误诊为纤维腺瘤。
Invasive Papillary Carcinoma of the Male Breast Misdiagnosed as Fibroadenoma on FNAB.
作者信息
Katiyar Richa, Patne Shashikant C U, Kumar Sandip, Khanna Rahul
机构信息
Service Senior Resident, Department of Pathology, Institute of Medical Sciences, Banaras Hindu University , Varanasi, Uttar Pradesh, India .
Assistant Professor, Department of Pathology, Institute of Medical Sciences, Banaras Hindu University , Varanasi, Uttar Pradesh, India .
出版信息
J Clin Diagn Res. 2017 Feb;11(2):ED06-ED07. doi: 10.7860/JCDR/2017/24832.9211. Epub 2017 Feb 1.
Male breast cancers constitute less than 1% of all the breast cancers. Papillary carcinoma is a very rare tumour of the male breast. Due to rarity, Fine Needle Aspiration Biopsy (FNAB) findings of papillary carcinoma in male breast are seldom reported. A 55-year-old male presented with a lump in the left breast of two years' duration. FNAB was reported as fibroadenoma. Histopathological examination of the excised breast lump revealed invasive papillary carcinoma. Immunohistochemistry showed expression of pancytokeratin, oestrogen receptor, and progesterone receptor. Negative immunostaining was seen for HER2, p53, 34βE12, and CD34. Ki-67 proliferative index was 5%. We have discussed cytological findings of invasive papillary carcinoma and its differential diagnoses. Cytopathologists must be aware of cytologic findings of invasive papillary carcinoma of the male breast.
男性乳腺癌占所有乳腺癌的比例不到1%。乳头状癌是男性乳腺非常罕见的肿瘤。由于其罕见性，男性乳腺乳头状癌的细针穿刺活检（FNAB）结果很少被报道。一名55岁男性因左侧乳房出现肿块两年前来就诊。FNAB报告为纤维腺瘤。对切除的乳房肿块进行组织病理学检查显示为浸润性乳头状癌。免疫组织化学显示全细胞角蛋白、雌激素受体和孕激素受体表达。HER2、p53、34βE12和CD34免疫染色均为阴性。Ki-67增殖指数为5%。我们讨论了浸润性乳头状癌的细胞学表现及其鉴别诊断。细胞病理学家必须了解男性乳腺浸润性乳头状癌的细胞学表现。
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