• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

植入型心律转复除颤器治疗患者的医疗保健利用情况分析:一项管理心室起搏试验的分析。

Characterization of health care utilization in patients receiving implantable cardioverter-defibrillator therapies: An analysis of the managed ventricular pacing trial.

机构信息

Cleveland Clinic Foundation, Cleveland Ohio.

Thomas Jefferson University, Philadelphia, Pennsylvania.

出版信息

Heart Rhythm. 2017 Sep;14(9):1382-1387. doi: 10.1016/j.hrthm.2017.03.040. Epub 2017 Apr 4.

DOI:10.1016/j.hrthm.2017.03.040
PMID:28385672
Abstract

BACKGROUND

Implantable cardioverter-defibrillators (ICDs) are effective in terminating lethal arrhythmias, but little is known about the degree of health care utilization (HCU) after ICD therapies.

OBJECTIVE

Using data from the managed ventricular pacing trial, we sought to identify the incidence and types of HCU in ICD patients after receiving ICD therapy (shocks or antitachycardia pacing [ATP]).

METHODS

We analyzed HCU events (ventricular tachyarrhythmia [VTA]-related, heart failure-related, ICD implant procedure-related, ICD system-related, or other) and their association with ICD therapies (shocked ventricular tachycardia episode, ATP-terminated ventricular tachycardia episode, and inappropriately shocked episode).

RESULTS

A total of 1879 HCUs occurred in 695 of 1030 subjects (80% primary prevention) and were classified as follows: 133 (7%) VTA-related, 373 (20%) heart failure-related, 97 (5%) implant procedure-related, 115 (6%) system-related, and 1160 (62%) other. Of 2113 treated VTA episodes, 1680 (80%) received ATP only and 433 (20%) received shocks. Stratifying VTA-related HCUs on the basis of the type of ICD therapy delivered, there were 25 HCUs per 100 shocked VTA episodes compared with 1 HCU per 100 ATP-terminated episodes. Inappropriate ICD shocks occurred in 8.7% of the subjects and were associated with 115 HCUs. The majority of HCUs (52%) began in the emergency department, and 66% of all HCUs resulted in hospitalization.

CONCLUSION

For VTA-related HCUs, shocks are associated with a 25-fold increase in HCUs compared to VTAs treated by ATP only. Application of evidence-based strategies and automated device-based algorithms to reduce ICD shocks (higher rate cutoffs, use of ATP, and arrhythmia detection) may help reduce HCUs.

摘要

背景

植入式心脏复律除颤器(ICD)可有效终止致命性心律失常,但对于 ICD 治疗后医疗保健利用(HCU)的程度知之甚少。

目的

本研究使用管理心室起搏试验的数据,旨在确定 ICD 治疗(电击或抗心动过速起搏[ATP])后 ICD 患者的 HCU 发生率和类型。

方法

我们分析了 HCU 事件(与室性心动过速[VTA]相关、与心力衰竭相关、与 ICD 植入程序相关、与 ICD 系统相关或其他)及其与 ICD 治疗(电击治疗的室性心动过速发作、ATP 终止的室性心动过速发作和不适当电击发作)的关联。

结果

在 1030 名受试者中的 695 名(80%为一级预防)中发生了 1879 次 HCU,分类如下:133 次(7%)与 VTA 相关,373 次(20%)与心力衰竭相关,97 次(5%)与植入程序相关,115 次(6%)与系统相关,1160 次(62%)与其他相关。在 2113 次治疗的 VTA 发作中,1680 次(80%)仅接受 ATP 治疗,433 次(20%)接受电击治疗。根据所给予的 ICD 治疗类型对 VTA 相关 HCU 进行分层,与每 100 次 ATP 终止的 VTA 发作相比,电击治疗的 VTA 发作每 100 次有 25 次 HCU。8.7%的受试者发生不适当的 ICD 电击,与 115 次 HCU 相关。大多数 HCU(52%)始于急诊科,66%的所有 HCU 导致住院。

结论

对于与 VTA 相关的 HCU,电击治疗与仅接受 ATP 治疗的 VTA 相比,HCU 增加了 25 倍。应用循证策略和基于设备的自动算法来减少 ICD 电击(更高的率截止值、使用 ATP 和心律失常检测)可能有助于减少 HCU。

相似文献

1
Characterization of health care utilization in patients receiving implantable cardioverter-defibrillator therapies: An analysis of the managed ventricular pacing trial.植入型心律转复除颤器治疗患者的医疗保健利用情况分析:一项管理心室起搏试验的分析。
Heart Rhythm. 2017 Sep;14(9):1382-1387. doi: 10.1016/j.hrthm.2017.03.040. Epub 2017 Apr 4.
2
Effect of long-detection interval vs standard-detection interval for implantable cardioverter-defibrillators on antitachycardia pacing and shock delivery: the ADVANCE III randomized clinical trial.长检测间隔与标准检测间隔对植入式心脏复律除颤器抗心动过速起搏和电击治疗效果的影响:ADVANCE III 随机临床试验。
JAMA. 2013 May 8;309(18):1903-11. doi: 10.1001/jama.2013.4598.
3
Outcomes of defibrillator therapy in catecholaminergic polymorphic ventricular tachycardia.儿茶酚胺能多形性室性心动过速的除颤治疗结果
Heart Rhythm. 2014 Jan;11(1):58-66. doi: 10.1016/j.hrthm.2013.10.027. Epub 2013 Oct 11.
4
A randomized study to compare ramp versus burst antitachycardia pacing therapies to treat fast ventricular tachyarrhythmias in patients with implantable cardioverter defibrillators: the PITAGORA ICD trial.一项比较斜坡式与猝发式抗心动过速起搏疗法治疗植入式心脏复律除颤器患者快速室性心律失常的随机研究:PITAGORA ICD试验
Circ Arrhythm Electrophysiol. 2009 Apr;2(2):146-53. doi: 10.1161/CIRCEP.108.804211. Epub 2009 Feb 13.
5
Differences in effects of electrical therapy type for ventricular arrhythmias on mortality in implantable cardioverter-defibrillator patients.不同电疗类型对植入式心脏复律除颤器患者室性心律失常死亡率的影响差异。
Heart Rhythm. 2010 Mar;7(3):353-60. doi: 10.1016/j.hrthm.2009.11.027. Epub 2009 Dec 2.
6
Increased Hospitalizations and Overall Healthcare Utilization in Patients Receiving Implantable Cardioverter-Defibrillator Shocks Compared With Antitachycardia Pacing.与抗心动过速起搏相比,接受植入式心脏复律除颤器电击的患者住院率和整体医疗保健利用率增加。
JACC Clin Electrophysiol. 2018 Feb;4(2):243-253. doi: 10.1016/j.jacep.2017.09.004. Epub 2017 Nov 15.
7
Efficacy and Safety of Appropriate Shocks and Antitachycardia Pacing in Transvenous and Subcutaneous Implantable Defibrillators: Analysis of All Appropriate Therapy in the PRAETORIAN Trial.经静脉和皮下植入式除颤器中适当电击和抗心动过速起搏的疗效和安全性:PRAETORIAN 试验中所有适当治疗的分析。
Circulation. 2022 Feb;145(5):321-329. doi: 10.1161/CIRCULATIONAHA.121.057816. Epub 2021 Nov 14.
8
Clinical course and prognostic relevance of antitachycardia pacing-terminated ventricular tachyarrhythmias in implantable cardioverter-defibrillator patients.植入式心脏复律除颤器患者中抗心动过速起搏终止的室性心律失常的临床过程和预后相关性。
Europace. 2015 Jul;17(7):1068-75. doi: 10.1093/europace/euv007. Epub 2015 Feb 16.
9
Survival after shock therapy in implantable cardioverter-defibrillator and cardiac resynchronization therapy-defibrillator recipients according to rhythm shocked. The ALTITUDE survival by rhythm study.根据电击节律对植入式心脏复律除颤器和心脏再同步治疗除颤器受者电击治疗后的生存情况。节律研究中的 ALTITUDE 生存情况。
J Am Coll Cardiol. 2013 Oct 29;62(18):1674-1679. doi: 10.1016/j.jacc.2013.04.083. Epub 2013 Jun 27.
10
Arrhythmic episodes in patients implanted with a cardioverter-defibrillator - results from the Prospective Study on Predictive Quality with Preferencing PainFree ATP therapies (4P).植入心脏转复除颤器患者的心律失常发作 - 来自前瞻性预测质量研究,首选无痛苦 ATP 治疗(4P)的结果。
BMC Cardiovasc Disord. 2019 Jun 17;19(1):146. doi: 10.1186/s12872-019-1121-4.

引用本文的文献

1
Healthcare utilization in patients with first-time implantable cardioverter defibrillators (data from the WEBCARE study).首次植入式心脏复律除颤器患者的医疗保健利用情况(来自WEBCARE研究的数据)。
Pacing Clin Electrophysiol. 2019 Apr;42(4):439-446. doi: 10.1111/pace.13636. Epub 2019 Mar 5.