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经皮球囊椎体后凸成形术治疗骨质疏松性隐匿性椎体骨折疼痛:89例回顾性研究

Percutaneous Balloon Kyphoplasty in Treatment of Painful Osteoporotic Occult Vertebral Fracture: A Retrospective Study of 89 Cases.

作者信息

Sun Zhi-Yong, Li Xue-Feng, Zhao Huan, Lin Jun, Qian Zhong-Lai, Zhang Zhi-Ming, Yang Hui-Lin

机构信息

Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China (mainland).

出版信息

Med Sci Monit. 2017 Apr 7;23:1682-1690. doi: 10.12659/msm.903997.

Abstract

BACKGROUND The definition of a vertebral fracture is usually based on the presence of a deformation of the vertebral body and this can be misleading in the presence of a fracture without radiologic collapse with the definition of occult osteoporotic vertebral fractures (OOVFs). STIR sequence of MRI images showing hyperintensity signal was the most confirmative screening examination used to determine the presence of painful OOVFs. To date, clinical management of OOVFs has been rarely discussed. MATERIAL AND METHODS Between 2011 and 2013, 89 patients suffering from painful OOVFs underwent 142 percutaneous balloon kyphoplasty (PKP) procedures. Outcome data (mean variation of anterior and middle vertebral body height, visual analog scale [VAS] scores, Oswestry Disability Index [ODI] scores, and SF-36 scores) were recorded preoperatively, postoperatively, and at 1 month, 6 months, and 2 year after treatment, to evaluate the results. RESULTS We successfully treated 89 patients (142 vertebral bodies) with PKP. Cement leakages were observed in 12 (8.45%) treated vertebral bodies and there were 5 new adjacent vertebral fractures during the follow-up period. The mean variation of anterior and middle vertebral body height changed from 96.5±3.4% preoperatively to 97.2±2.5% postoperatively (p>0.05) and from 96.3±2.8% preoperatively to 97.9±3.1% postoperatively (p>0.05), respectively. The mean VAS scores were reduced significantly from pre-surgery to post-surgery (8.3±1.2 to 2.9±0.7; p<0.05), as was the ODI score (76.4±12.5 to 26.7±5.6; p<0.05). The SF-36 scores, including Bodily Pain (BF), Vitality (VT), Physical Function (PF), and Social Functioning (SF), all showed notable improvement (P<0.05). These variations were maintained during the 2-year follow-up period. CONCLUSIONS PKP is a safe and effective method in the treatment of painful OOVFs.

摘要

背景

椎体骨折的定义通常基于椎体变形的存在,而在存在无放射学塌陷的骨折(即隐匿性骨质疏松性椎体骨折,OOVFs)时,这可能会产生误导。MRI图像的短TI反转恢复(STIR)序列显示高信号是用于确定疼痛性OOVFs存在的最具确诊性的筛查检查。迄今为止,很少讨论OOVFs的临床管理。

材料与方法

在2011年至2013年期间,89例患有疼痛性OOVFs的患者接受了142次经皮球囊椎体后凸成形术(PKP)。记录术前、术后以及治疗后1个月、6个月和2年的结果数据(椎体前、中高度的平均变化、视觉模拟量表[VAS]评分、Oswestry功能障碍指数[ODI]评分和SF-36评分),以评估结果。

结果

我们成功地用PKP治疗了89例患者(142个椎体)。在12个(8.45%)治疗的椎体中观察到骨水泥渗漏,随访期间有5例新发相邻椎体骨折。椎体前、中高度的平均变化分别从术前的96.5±3.4%变为术后的97.2±2.5%(p>0.05),以及从术前的96.3±2.8%变为术后的97.9±3.1%(p>0.05)。平均VAS评分从术前到术后显著降低(8.3±1.2至2.9±0.7;p<0.05),ODI评分也是如此(76.4±12.5至26.7±5.6;p<0.05)。SF-36评分,包括身体疼痛(BF)、活力(VT)、身体功能(PF)和社会功能(SF),均显示出显著改善(P<0.05)。这些变化在2年的随访期内得以维持。

结论

PKP是治疗疼痛性OOVFs的一种安全有效的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7c2/5391800/3d60421f0bd1/medscimonit-23-1682-g001.jpg

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