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[电子烟:毒理学方面的科学现状]

[Electronic cigarette : state of the science about toxicological aspects].

作者信息

Deville M, Charlier C

机构信息

Service de Toxicologie Clinique, Médico-légale, de l'Environnement et en Entreprise, CHU de Liège, site Sart Tilman, Belgique.

Centre Interfacultaire de Recherche du Médicament, Département de Pharmacie, Université de Liège, Belgique.

出版信息

Rev Med Liege. 2017 Jan;72(1):20-24.

PMID:28387073
Abstract

Electronic cigarettes (e-cigarettes) are presented as a healthier alternative to tobacco smoking. They are designed to contain a solution which is heated to produce an aerosol inhaled by the user. The liquid is mainly composed of propylene glycol, glycerol, flavours and, in some cases, nicotine. Except for nicotine, which can be fatal when ingested at high dose, these components are generally considered as safe. However, the potential effect of long term exposure to inhaled propylene glycol is unknown at this time. As an advantage, toxic compounds responsible for the noxiousness of tobacco smoking (nitrosamines, metals, formaldehyde, carbon monoxide …) are either absent, or present in the smoke of e-cigarette at levels far less compared to conventional cigarette smoke. Finally, efficacy of e-cigarette as a tool for smoking cessation stays to be proven.

摘要

电子烟被视为比吸烟更健康的选择。它们的设计是含有一种溶液,该溶液被加热以产生供使用者吸入的气溶胶。这种液体主要由丙二醇、甘油、香料组成,在某些情况下还含有尼古丁。除了尼古丁在高剂量摄入时可能致命外,这些成分通常被认为是安全的。然而,目前长期接触吸入丙二醇的潜在影响尚不清楚。一个优点是,导致吸烟有害的有毒化合物(亚硝胺、金属、甲醛、一氧化碳等)在电子烟烟雾中要么不存在,要么其含量与传统香烟烟雾相比要低得多。最后,电子烟作为戒烟工具的效果还有待证实。

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