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EULAR 外周关节骨关节炎临床管理中影像学应用的推荐。

EULAR recommendations for the use of imaging in the clinical management of peripheral joint osteoarthritis.

机构信息

Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, University of Pavia, Pavia, Italy.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and National Institute of Health Research Leeds Musculoskeletal Biomedical Research Unit, Leeds, UK.

出版信息

Ann Rheum Dis. 2017 Sep;76(9):1484-1494. doi: 10.1136/annrheumdis-2016-210815. Epub 2017 Apr 7.

Abstract

The increased information provided by modern imaging has led to its more extensive use. Our aim was to develop evidence-based recommendations for the use of imaging in the clinical management of the most common arthropathy, osteoarthritis (OA). A task force (including rheumatologists, radiologists, methodologists, primary care doctors and patients) from nine countries defined 10 questions on the role of imaging in OA to support a systematic literature review (SLR). Joints of interest were the knee, hip, hand and foot; imaging modalities included conventional radiography (CR), MRI, ultrasonography, CT and nuclear medicine. PubMed and EMBASE were searched. The evidence was presented to the task force who subsequently developed the recommendations. The strength of agreement for each recommendation was assessed. 17 011 references were identified from which 390 studies were included in the SLR. Seven recommendations were produced, covering the lack of need for diagnostic imaging in patients with typical symptoms; the role of imaging in differential diagnosis; the lack of benefit in monitoring when no therapeutic modification is related, though consideration is required when unexpected clinical deterioration occurs; CR as the first-choice imaging modality; consideration of how to correctly acquire images and the role of imaging in guiding local injections. Recommendations for future research were also developed based on gaps in evidence, such as the use of imaging in identifying therapeutic targets, and demonstrating the added value of imaging. These evidence-based recommendations and related research agenda provide the basis for sensible use of imaging in routine clinical assessment of people with OA.

摘要

现代影像学提供的信息增加,导致其应用更加广泛。我们的目的是为最常见的关节病骨关节炎(OA)的临床管理中影像学的应用制定基于证据的推荐意见。来自九个国家的一个工作组(包括风湿病学家、放射科医生、方法学家、初级保健医生和患者)定义了 10 个关于影像学在 OA 中的作用的问题,以支持系统文献综述(SLR)。感兴趣的关节包括膝关节、髋关节、手和脚;影像学方式包括常规放射摄影(CR)、MRI、超声、CT 和核医学。在 PubMed 和 EMBASE 上进行了搜索。将证据提交给工作组,随后工作组制定了建议。对每项建议的一致性强度进行了评估。从 17011 篇参考文献中,纳入了 390 项研究进行 SLR。提出了 7 项建议,涵盖了以下内容:对于有典型症状的患者,无需进行诊断性影像学检查;影像学在鉴别诊断中的作用;在没有治疗改变相关的情况下,监测没有益处,但当出现意外临床恶化时需要考虑;CR 作为首选影像学方式;考虑如何正确获取图像以及影像学在引导局部注射中的作用。还根据证据中的空白制定了未来研究的建议,例如影像学在确定治疗靶点和展示影像学的附加价值方面的应用。这些基于证据的建议和相关的研究议程为 OA 患者常规临床评估中合理使用影像学提供了依据。

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