Cha Wang Woon, Song Kudamo, Yu In Kyu, Choi Myoung Su, Chang Dong Sik, Cho Chin-Saeng, Lee Ho Yun
Department of Otorhinolaryngology, Eulji University Medical Center, Eulji University School of Medicine, Daejeon, Republic of Korea.
Department of Diagnostic Radiology, Eulji University Medical Center, Eulji University School of Medicine, Eulji University, Daejeon, Republic of Korea.
Am J Otolaryngol. 2017 Jul-Aug;38(4):428-432. doi: 10.1016/j.amjoto.2017.04.001. Epub 2017 Apr 4.
We aimed to evaluate the clinical implications of magnetic resonance imaging (MRI) findings in patients with benign paroxysmal positional vertigo (BPPV).
A total of 120 patients diagnosed with BPPV completed MRI at the emergency room between December 2012 and June 2015 and met our criteria for inclusion in this study. Epidemiologic characteristics, the results of audio-vestibular testing, and MRI findings were retrospectively analyzed.
The most common findings were white matter hyperintensities (70.0%), sinusitis (34.2%), and brain atrophy (25.0%). There were no significant differences in MRI findings or epidemiologic characteristics according to BPPV subtype (p>0.05). A multiple regression analysis revealed that BPPV recurrence (odds ratio, 6.88; 95% confidence interval, 1.67-34.48; p=0.009) and brain atrophy (odds ratio, 4.39; 95% confidence interval, 1.11-21.28; p=0.036) were positively associated with dizziness lasting longer than 3months.
Brain atrophy was independently associated with long-lasting dizziness after BPPV. Although the mechanism is unclear, brain atrophy may have relevance to otoneurotologic disease-related changes in brain structure.
我们旨在评估良性阵发性位置性眩晕（BPPV）患者磁共振成像（MRI）检查结果的临床意义。
2012年12月至2015年6月期间，共有120例确诊为BPPV的患者在急诊室完成了MRI检查，并符合本研究的纳入标准。对其流行病学特征、听-前庭测试结果和MRI检查结果进行回顾性分析。
最常见的检查结果为白质高信号（70.0%）、鼻窦炎（34.2%）和脑萎缩（25.0%）。根据BPPV亚型，MRI检查结果或流行病学特征无显著差异（p>0.05）。多元回归分析显示，BPPV复发（比值比，6.88；95%置信区间，1.67-34.48；p=0.009）和脑萎缩（比值比，4.39；95%置信区间，1.11-21.28；p=0.036）与持续超过3个月的头晕呈正相关。
脑萎缩与BPPV后长期头晕独立相关。虽然机制尚不清楚，但脑萎缩可能与耳神经学疾病相关的脑结构变化有关。
