Plata M, Caicedo J I, Trujillo C G, Mariño-Alvarez Á M, Fernandez N, Gutierrez A, Godoy F, Cabrera M, Cataño-Cataño J G, Robledo D
Departamento de Urología, Hospital Universitario de la Fundación Santa Fe de Bogotá, Bogotá D.C., Colombia; Facultad de Medicina de la Universidad de los Andes, Bogotá D.C., Colombia.
Departamento de Urología, Hospital Universitario de la Fundación Santa Fe de Bogotá, Bogotá D.C., Colombia; Facultad de Medicina de la Universidad de los Andes, Bogotá D.C., Colombia.
Actas Urol Esp. 2017 Oct;41(8):522-528. doi: 10.1016/j.acuro.2016.12.009. Epub 2017 Apr 5.
To estimate the frequency of metabolic syndrome (MetS) in a daily urology practice and to determine its association with lower urinary tract symptoms (LUTS) and erectile dysfunction (ED).
A retrospective study was conducted. Data from all male patients aged ≥40 years who attended our outpatient urology clinic from 2010 to 2011 was collected. Prevalence of MetS was determined, and LUTS and ED were assessed. A logistic model was used to determine possible associations, controlling for confounders and interaction factors.
A total of 616 patients were included. MetS was observed in 43.8% (95% CI 39.6-48.3). The bivariate model showed an association between MetS and LUTS (p<0.01), but not between MetS and ED. The logistic model showed an association between MetS and the International Prostate Symptom Score (IPSS), while controlling for other variables. Patients exhibiting moderate LUTS had a greater risk for MetS than patients with mild LUTS (OR 1.83, 95% CI 1.14-2.94). After analyzing for individual components of MetS, positive associations were found between diabetes and severe LUTS (OR 1.3, 95% CI 1.24-7.1), and between diabetes and ED (OR 2.57, 95% CI 1.12-5.8).
This study was able to confirm an association between MetS and LUTS, but not for ED. Specific components such as diabetes were associated to both. Geographical differences previously reported in the literature might account for these findings. Given that MetS is frequent among urological patients, it is advisable that urologists actively screen for it.
评估日常泌尿外科诊疗中代谢综合征（MetS）的发生率，并确定其与下尿路症状（LUTS）及勃起功能障碍（ED）之间的关联。
开展一项回顾性研究。收集了2010年至2011年期间在我院泌尿外科门诊就诊的所有年龄≥40岁男性患者的数据。确定MetS的患病率，并评估LUTS和ED。采用逻辑模型确定可能的关联，同时控制混杂因素和交互因素。
共纳入616例患者。观察到MetS的发生率为43.8%（95%可信区间39.6 - 48.3）。双变量模型显示MetS与LUTS之间存在关联（p<0.01），但MetS与ED之间无关联。逻辑模型显示在控制其他变量的情况下，MetS与国际前列腺症状评分（IPSS）之间存在关联。表现为中度LUTS的患者患MetS的风险高于轻度LUTS患者（比值比1.83，95%可信区间1.14 - 2.94）。在分析MetS的各个组成部分后，发现糖尿病与重度LUTS之间存在正相关（比值比1.3，95%可信区间1.24 - 7.1），以及糖尿病与ED之间存在正相关（比值比2.57，95%可信区间1.12 - 5.8）。
本研究能够证实MetS与LUTS之间存在关联，但与ED无关。糖尿病等特定组成部分与两者均有关联。文献中先前报道的地理差异可能解释了这些结果。鉴于MetS在泌尿外科患者中很常见，建议泌尿外科医生积极筛查。
