Sargent James D, Gabrielli Joy, Budney Alan, Soneji Samir, Wills Thomas A
C Everett Koop Institute, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, United States.
Department of Data Science, Geisel School of Medicine at Dartmouth, United States.
Drug Alcohol Depend. 2017 Jun 1;175:55-59. doi: 10.1016/j.drugalcdep.2017.01.038. Epub 2017 Mar 28.
The utility of studying substance use during early adolescence depends on how well indicies of lower-level experimentation predict the development of substance use problems. We examined associations between experimental cigarette use at T1, recanting of use 8 months later (T2), and daily smoking at 2 years (T4).
Longitudinal telephone survey of 6522 US youth aged 10-14, examining lifetime cigarette smoking (none, just puffing, 1-19, 20-100, >100) and recanting (i.e., reporting lifetime use at T1, denying ever using at T2) as predictors of T4 daily smoking using multivariable logistic regression. Covariates included sociodemographics, friend/family smoking, school performance, and personality characteristics.
The sample was 51% male, 18% Black, 17% Hispanic, with 70% retained at T2. At T1, 407 (8.9%) adolescents reported some smoking, of whom 85 (20.9%) recanted at T2. At T4, 970 reported any smoking, of whom 88 (9.1%) were daily smokers. Any T1 experimentation identified two-thirds of T4 daily smokers (sensitivity=66.7%) with a false positive rate of 7.8%. T1 lifetime smoking categories were associated with the following adjusted odds ratios for T4 daily smoking (vs. never smokers): 2.7 for recanters (95% confidence interval 0.82, 8.5), 3.5 for few puffs (1.7, 7.0), 9.6 for 1-19 cigarettes (4.1, 22.3), 3.8 for 20-100 cigarettes (1.0, 14.3), and 30.1 for >100 cigarettes (8.1, 111).
In this sample experimentation with cigarettes predicted future daily smoking with high utility. The findings provide a rationale for monitoring and reporting any experimentation cigarettes as a tobacco surveillance outcome.
研究青春期早期物质使用情况的效用取决于较低水平尝试的指标对物质使用问题发展的预测能力。我们研究了T1时尝试吸烟、8个月后(T2)不再承认吸烟与2年后(T4)每日吸烟之间的关联。
对6522名10 - 14岁美国青少年进行纵向电话调查,使用多变量逻辑回归分析终生吸烟情况(从不吸烟、仅吸过几口、吸过1 - 19支、吸过20 - 100支、吸过超过100支)以及不再承认吸烟(即在T1报告终生吸烟,在T2否认曾吸烟)作为T4每日吸烟的预测因素。协变量包括社会人口统计学特征、朋友/家人吸烟情况、学业成绩和性格特征。
样本中51%为男性,18%为黑人,17%为西班牙裔,70%在T2时仍被随访。在T1时,407名(8.9%)青少年报告有过吸烟,其中85名(20.9%)在T2时不再承认吸烟。在T4时,970名报告有过吸烟,其中88名(9.1%)为每日吸烟者。T1时的任何尝试吸烟行为可识别出三分之二的T4每日吸烟者(敏感性 = 66.7%),假阳性率为7.8%。T1时的终生吸烟类别与T4每日吸烟的以下调整后比值比相关(与从不吸烟者相比):不再承认吸烟者为2.7(95%置信区间0.82,8.5),仅吸过几口者为3.5(1.7,7.0),吸过1 - 19支者为9.6(4.1,22.3),吸过20 - 100支者为3.8(1.0,14.3),吸过超过100支者为30.1(8.1,111)。
在该样本中,尝试吸烟对未来每日吸烟具有较高的预测效用。这些发现为将任何尝试吸烟行为作为烟草监测结果进行监测和报告提供了理论依据。