沙特阿拉伯潜伏性结核分枝杆菌感染（LTBI）的患病率；基于人群的调查。
Prevalence of Latent Mycobacterium Tuberculosis Infection (LTBI) in Saudi Arabia; Population based survey.
作者信息
Balkhy Hanan H, El Beltagy Kamel, El-Saed Aiman, Aljasir Badr, Althaqafi Abdulhakeem, Alothman Adel F, Alshalaan Mohammad, Al-Jahdali Hamdan
机构信息
King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Kingdom of Saudi Arabia; King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs, Kingdom of Saudi Arabia; Infection Prevention and Control Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Saudi Arabia.
Infection Prevention and Control Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Saudi Arabia; Public health & Community Medicine Department, Faculty of Medicine, Tanta University, Egypt.
出版信息
Int J Infect Dis. 2017 Jul;60:11-16. doi: 10.1016/j.ijid.2017.03.024. Epub 2017 Apr 6.
BACKGROUND
The annual risk of tuberculosis infection (ARTI) data in Saudi Arabia has not been updated since 1993.
OBJECTIVES
To estimate the prevalence of latent TB infection (LTBI) and ARTI in a population-based sample in Saudi Arabia using Tuberculin skin test (TST) and QuantiFERON TB Gold in tube (QFT-GIT) test.
METHODS
A population-based cross sectional study was conducted between July 2010 and March 2013. Participants were randomly selected from the population served by the primary healthcare centers of the Ministry of National Guard Health Affairs in Riyadh, Jeddah, Alhassa and Dammam, Saudi Arabia.
RESULTS
A total of 1369 participants were included. The overall prevalence of LTBI was similar using TST and QFT-GIT (9.3% and 9.1% respectively, p=0.872) but stratified prevalence rates were variable in all sociodemographic groups except marital status. Additionally, the prevalence rates of LTBI using either test alone showed significant differences by several sociodemographic and behavioral characteristics. The overall ARTI was 0.36% using TST and 0.35% using QFT-GIT.
CONCLUSIONS
We are reporting much lower estimates for the prevalence of LTBI and the ARTI in a population-based sample in Saudi Arabia relative to the data that have been used for more than two decades.
背景
沙特阿拉伯自1993年以来尚未更新结核病感染年度风险（ARTI）数据。
目的
使用结核菌素皮肤试验（TST）和全血γ-干扰素释放试验（QFT-GIT）估计沙特阿拉伯基于人群样本中的潜伏性结核感染（LTBI）患病率和ARTI。
方法
2010年7月至2013年3月进行了一项基于人群的横断面研究。参与者从沙特阿拉伯利雅得、吉达、哈萨和达曼国民警卫队卫生事务部初级保健中心服务的人群中随机选取。
结果
共纳入1369名参与者。使用TST和QFT-GIT时LTBI的总体患病率相似（分别为9.3%和9.1%，p = 0.872），但除婚姻状况外，所有社会人口学组的分层患病率各不相同。此外，单独使用任何一种检测方法时，LTBI的患病率在几个社会人口学和行为特征方面存在显著差异。使用TST时总体ARTI为0.36%，使用QFT-GIT时为0.35%。
结论
相对于二十多年来一直使用的数据，我们报告的沙特阿拉伯基于人群样本中的LTBI患病率和ARTI估计值要低得多。
Zotero 插件