患有阻塞性睡眠呼吸暂停的伊朗患者心血管疾病的患病率
Prevalence of Cardiovascular Disorders in Iranian Patients Suffering from Obstructive Sleep Apnea.
作者信息
Shirani Gholamreza, Morovati Seyyedeh Pouya, Shamshiri Ahmad Reza, Nouri Mehdi, Givi Narges Ezzati, Farhadi Mohammad
机构信息
Assistant Professor, Department of Oral and Maxillofacial Surgery, Craniomaxillofacial Research Center, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Assistant Professor, Department of Pediatric Dentistry, School of Dentistry, Kurdistan University of Medical Sciences, Sanandaj, Iran.
出版信息
J Dent (Tehran). 2016 Jun;13(3):151-156.
OBJECTIVES
Obstructive sleep apnea (OSA) can lead to various cardiovascular disorders (CVD) such as hypertension. There is no documented data about this relationship among the Iranian population. The aim of this study was to obtain comprehensive information about the severity of OSA as a cause of CVD and its relationship with other important risk factors.
MATERIALS AND METHODS
In this cross sectional study, we studied patients with OSA and apnea/hypopnea index of 5 or more. The data were collected from the patients' polysomnography report and medical files. Data analysis was done with SPSS version 18.
RESULTS
The majority of patients were males (71.9%). Among the studied individuals, 26.5% showed at least one sign of CVD, and hypertension was the most common condition (74.5%). Multiple regression analysis showed that the odds ratios for one unit increase in BMI and one year increase in age were 1.13 and 1.12, respectively (P<0.001).
CONCLUSIONS
In our study, BMI and age had the strongest relationship with CVD. Thus, public health care providers should implement weight control strategies and improve diagnostic and treatment procedures for the elderly patients.
目的
阻塞性睡眠呼吸暂停（OSA）可导致多种心血管疾病（CVD），如高血压。在伊朗人群中，尚无关于这种关系的文献记载数据。本研究的目的是获取有关作为心血管疾病病因的阻塞性睡眠呼吸暂停严重程度及其与其他重要危险因素关系的全面信息。
材料与方法
在这项横断面研究中，我们研究了呼吸暂停低通气指数为5或更高的阻塞性睡眠呼吸暂停患者。数据从患者的多导睡眠图报告和医疗档案中收集。使用SPSS 18版进行数据分析。
结果
大多数患者为男性（71.9%）。在研究对象中，26.5%表现出至少一种心血管疾病体征，高血压是最常见的病症（74.5%）。多元回归分析表明，体重指数每增加一个单位和年龄每增加一岁的优势比分别为1.13和1.12（P<0.001）。
结论
在我们的研究中，体重指数和年龄与心血管疾病的关系最为密切。因此，公共卫生保健提供者应实施体重控制策略，并改善老年患者的诊断和治疗程序。
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