Levine Ellen G, Yoo Grace, Aviv Caryn
Walden University.
San Francisco State University.
Appl Res Qual Life. 2017 Mar;12(1):1-16. doi: 10.1007/s11482-016-9447-x. Epub 2016 Jan 28.
Few studies have examined predictors of quality of life (QOL) of breast cancer survivors over time.
Breast cancer survivors (n=116) were asked to complete measures of QOL, mood, spirituality, and social support every 6 months from 2-4 years post treatment.
Overall QOL at 4 years was predicted by previous physical and functional well-being, the breast cancer-specific items, and vigor and current levels of social support (Adj R=.72, F=30.53, p<.001). Physical QOL was predicted by previous levels of physical and functional well- being and current levels of functional and social/family well-being (Adj R=.84, F=44.30, p<.001). Functional well- being was predicted by prior levels of physical, functional, and social/family well-being and current levels of physical well-being and vigor (Adj R=.72, F=3-.53, p<.001). Emotional well-being was predicted by previous levels of emotional well-being and current physical well-being, the breast cancer-specific items, and anxiety (Adj R=.60, F=26.30, p<.001). Social/family well-being was predicted by previous levels of social/family well-being, social support, and confusion (Adj R=.71, F=34.18, p<<000). The breast cancer-specific items were predicted by age, previous levels of the breast cancer-specific items, confusion and current levels of emotional and functional well-being and spirituality (Adj R=.58, F=17.57, p<.001).
Over all and specific dimensions of QOL at 4 years were predicted by different combinations of QOL, mood, and spirituality. Interventions should be tailored to which dimensions of QOL are affected and other types of QOL as well as social support, mood, and spirituality as coping mechanisms that influence the specific dimension of QOL affected.
很少有研究探讨乳腺癌幸存者生活质量(QOL)随时间变化的预测因素。
乳腺癌幸存者(n = 116)被要求在治疗后2至4年期间,每6个月完成一次生活质量、情绪、精神状态和社会支持的测量。
4年时的总体生活质量由先前的身体和功能健康状况、乳腺癌特定项目、活力以及当前的社会支持水平预测(调整R = 0.72,F = 30.53,p < 0.001)。身体生活质量由先前的身体和功能健康水平以及当前的功能和社会/家庭健康水平预测(调整R = 0.84,F = 44.30,p < 0.001)。功能健康由先前的身体、功能和社会/家庭健康水平以及当前的身体状况和活力预测(调整R = 0.72,F = 30.53,p < 0.001)。情绪健康由先前的情绪健康水平、当前的身体状况、乳腺癌特定项目和焦虑预测(调整R = 0.60,F = 26.30,p < 0.001)。社会/家庭健康由先前的社会/家庭健康水平、社会支持和困惑预测(调整R = 0.71,F = 34.18,p < <0.000)。乳腺癌特定项目由年龄、先前的乳腺癌特定项目水平、困惑以及当前的情绪、功能健康和精神状态水平预测(调整R = 0.58,F = 17.57,p < 0.001)。
4年时生活质量的总体和特定维度由生活质量、情绪和精神状态的不同组合预测。干预措施应根据生活质量受影响的维度以及其他类型的生活质量,以及作为影响生活质量特定维度的应对机制的社会支持、情绪和精神状态进行调整。