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非体外循环下心肌血运重建;为何尚未令人信服?

Myocardial revascularization without extracorporeal circulation; Why hasn't it convinced yet?

作者信息

Apostolakis Efstratios, Papakonstantinou Nikolaos A, Koniari Ioanna

机构信息

Department of Cardiothoracic Surgery, University Hospital of Ioannina, School of Medicine, 45500 Ioannina, Greece.

Department of Cardiothoracic Surgery, General Hospital of Athens "Evangelismos", Athens, Greece.

出版信息

Ann Card Anaesth. 2017 Apr-Jun;20(2):219-225. doi: 10.4103/aca.ACA_39_16.

Abstract

Extracorporeal circulation has led to a great development in cardiovascular surgery during the last five decades. Its time-proven efficacy and safety have made on-pump coronary artery bypass grafting (CABG) the gold standard method of surgical revascularization. However, coronary revascularization on cardiopulmonary bypass and the accompanying aortic manipulation are related to plenty of deleterious complications. Therefore, off-pump CABG surgery was established to avoid complications. Nevertheless, despite the initial enthusiasm on this technique, only 20% of myocardial revascularization procedures worldwide are performed off-pump. Not only are off-pump cardiac procedures more technically difficult but also they do not provide better results in terms of graft patency, completeness of revascularization, repeat revascularization requirement, cost, and quality of life. Completeness of revascularization and anastomotic quality should not be compromised to avoid cardiopulmonary bypass.

摘要

在过去的五十年里,体外循环推动了心血管外科的巨大发展。其经过时间验证的疗效和安全性已使体外循环冠状动脉旁路移植术(CABG)成为外科血运重建的金标准方法。然而,体外循环下的冠状动脉血运重建以及随之而来的主动脉操作与大量有害并发症相关。因此,非体外循环CABG手术应运而生以避免并发症。尽管如此,尽管最初人们对该技术充满热情,但全球仅20%的心肌血运重建手术是在非体外循环下进行的。非体外循环心脏手术不仅技术难度更大,而且在移植血管通畅性、血运重建完整性、再次血运重建需求、成本和生活质量方面也未带来更好的结果。不应为了避免体外循环而牺牲血运重建的完整性和吻合质量。

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