Urbanowicz Tomasz, Olasińska-Wiśniewska Anna, Gładki Marcin, Jemielity Marek
Cardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, 61-848 Poznan, Poland.
Pediatric Cardiac Surgery Department, Poznan University of Medical Sciences, 60-572 Poznan, Poland.
Rev Cardiovasc Med. 2022 Dec 9;23(12):400. doi: 10.31083/j.rcm2312400. eCollection 2022 Dec.
The inflammatory background of coronary artery disease is gaining more attention in recent times. Off pump surgery is minimally invasive type of surgical revascularization with relatively low number of applications in cardiac surgery centers worldwide that allows for perioperative inflammatory reactions minimalization. The simple inflammatory markers (neutrophil to lymphocyte ratio (NLR), monocyte to lymphocyte ratio (MLR), platelets to lymphocyte ratio (PLR), systemic inflammatory index (SII), systemic inflammatory response index (SIRI), aggregate index of systemic inflammation (AISI)) possess a clinically significant impact on patients' prognosis and may help to improve patients' long-term results. The review presents the current knowledge regarding their utility in clinical practice. Assessment of inflammatory indices obtained from whole blood count analysis allows to indicate those patients who need scrupulous follow-up due to predicted worse long-term survival. Perioperative measurement and analysis of simple whole blood counts is inexpensive and easily available and may improve the results of surgical revascularization by better identification of patients at higher risk of worse outcomes.
近年来,冠状动脉疾病的炎症背景越来越受到关注。非体外循环手术是一种微创的外科血管重建术,在全球心脏外科中心的应用相对较少,它能使围手术期炎症反应降至最低。简单的炎症标志物(中性粒细胞与淋巴细胞比率(NLR)、单核细胞与淋巴细胞比率(MLR)、血小板与淋巴细胞比率(PLR)、全身炎症指数(SII)、全身炎症反应指数(SIRI)、全身炎症综合指数(AISI))对患者的预后具有临床显著影响,可能有助于改善患者的长期治疗效果。本综述介绍了目前关于它们在临床实践中效用的知识。通过全血细胞计数分析获得的炎症指标评估,有助于识别那些因预测长期生存率较差而需要严格随访的患者。围手术期简单全血细胞计数的测量和分析成本低廉且易于进行,通过更好地识别预后较差风险较高的患者,可能会改善外科血管重建术的治疗效果。