Postal M, Lapa A Tamires, Reis F, Rittner L, Appenzeller S
1 Autoimmunity Lab, State University of Campinas, Brazil.
2 Department of Neurology, State University of Campinas, Brazil.
Lupus. 2017 Apr;26(5):517-521. doi: 10.1177/0961203317691373.
Systemic lupus erythematosus is a chronic, inflammatory, immune-mediated disease affecting 0.1% of the general population. Neuropsychiatric manifestations in systemic lupus erythematosus have been more frequently recognized and reported in recent years, occurring in up to 75% of patients during the disease course. Magnetic resonance imaging is known to be a useful tool for the detection of structural brain abnormalities in neuropsychiatric systemic lupus erythematosus patients because of the excellent soft-tissue contrast observed with MRI and the ability to acquire multiplanar images. In addition to conventional magnetic resonance imaging techniques to evaluate the presence of atrophy and white matter lesions, several different magnetic resonance imaging techniques have been used to identify microstructural or functional abnormalities. This review will highlight different magnetic resonance imaging techniques, including the advanced magnetic resonance imaging methods used to determine central nervous system involvement in systemic lupus erythematosus.
系统性红斑狼疮是一种慢性、炎症性、免疫介导的疾病，影响着0.1%的普通人群。近年来，系统性红斑狼疮的神经精神表现得到了更频繁的认识和报道，在疾病过程中高达75%的患者会出现。由于MRI观察到的出色软组织对比度以及获取多平面图像的能力，磁共振成像已知是检测神经精神性系统性红斑狼疮患者脑结构异常的有用工具。除了用于评估萎缩和白质病变存在的传统磁共振成像技术外，还使用了几种不同的磁共振成像技术来识别微观结构或功能异常。本综述将重点介绍不同的磁共振成像技术，包括用于确定系统性红斑狼疮中枢神经系统受累情况的先进磁共振成像方法。
