Buy J N, Ghossain M A, Poirson F, Bazot M, Meary E, Malbec L, Rochemaure J, Lebeau B, Prudent J, Capron F
Department of Radiology, Hôtel Dieu, Paris, France.
J Comput Assist Tomogr. 1988 Jul-Aug;12(4):545-52. doi: 10.1097/00004728-198807000-00001.
Computed tomography was used to evaluate mediastinal lymph nodes in 97 patients with nonsmall cell lung cancer. All patients had thorough surgical-pathological determination of mediastinal node status. Twenty-three patients were found to have metastatic lymph nodes. The usual lymphatic pathways of tumor spread into the mediastinum were defined using the node mapping scheme suggested by the American Thoracic Society. We considered mediastinal nodes abnormal when the short axis of the largest mediastinal node in the lymphatic drainage territory of the cancer was greater than or equal to 10 mm and the difference between this node and the largest node in the other territories is greater than 5 mm. The sensitivity was 78%, the specificity 99%, the positive predictive value 95%, the negative predictive value 94%, and the accuracy 94%. Comparing our method to those that used the size criterion alone, the number of false positives was reduced.
计算机断层扫描用于评估97例非小细胞肺癌患者的纵隔淋巴结。所有患者均对纵隔淋巴结状态进行了全面的手术病理判定。发现23例患者有转移性淋巴结。采用美国胸科学会建议的淋巴结图谱方案确定肿瘤扩散至纵隔的常见淋巴途径。当癌症淋巴引流区域最大纵隔淋巴结的短轴大于或等于10毫米，且该淋巴结与其他区域最大淋巴结的差值大于5毫米时，我们认为纵隔淋巴结异常。敏感性为78%，特异性为99%，阳性预测值为95%，阴性预测值为94%，准确性为94%。与仅使用大小标准的方法相比，我们的方法减少了假阳性的数量。
