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急性白血病患者血清铜与骨髓原始细胞之间的关系

Relationship between serum copper and bone marrow blasts in acute leukaemia.

作者信息

Legutko L

出版信息

Haematologia (Budap). 1977;11(3-4):297-300.

PMID:283968
Abstract

Investigation of serum copper level (SCL) and bone marrow obtained on the same day from 45 children with acute lymphoblastic leukaemia (ALL) showed a highly significant correlation between SCL and marrow blasts. The increase of SCL was associated with the progress of ALL and the elevation of the marrow parablast percentage. The highest mean SCL level was observed in cases displaying full marrow involvement with concomitant hyperleukocytosis and/or leukaemic tumours. These observations suggest that SCL can be useful in the management of children with acute leukemia.

摘要

对45例急性淋巴细胞白血病(ALL)患儿同一天采集的血清铜水平(SCL)和骨髓进行的研究显示,SCL与骨髓原始细胞之间存在高度显著的相关性。SCL的升高与ALL的进展以及骨髓原幼细胞百分比的升高有关。在显示全骨髓受累并伴有白细胞增多和/或白血病肿瘤的病例中观察到最高的平均SCL水平。这些观察结果表明,SCL在急性白血病患儿的治疗中可能有用。

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