Desvignes C, Becquart C, Launay D, Terriou L, Patenotre P, Deheul S, Peytavin G, Dupin N, Delaporte E, Staumont-Sallé D
Department of Dermatology, Lille University Medical Centre, Claude Huriez Hospital, Lille, France.
Department of Internal Medicine, Lille University Medical Centre, Claude Huriez Hospital, Lille, France.
Clin Exp Dermatol. 2017 Jun;42(4):413-415. doi: 10.1111/ced.13085. Epub 2017 Apr 10.
Levamisole (an increasingly frequent contaminant of cocaine) can cause antineutrophil cytoplasmic antibody-associated vasculitis. Dermatologists should consider a diagnosis of cocaine/levamisole-associated cutaneous vasculopathy syndrome in cases of purpura of the ears and/or extensive retiform purpura in drug users. We report a case of particularly severe levamisole-induced necrotic purpura and immunological abnormalities in a 40-year-old woman.