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术前药物诱导睡眠内镜检查改善阻塞性睡眠呼吸暂停的手术治疗方法。

Preoperative Drug Induced Sleep Endoscopy Improves the Surgical Approach to Treatment of Obstructive Sleep Apnea.

作者信息

Huntley Colin, Chou David, Doghramji Karl, Boon Maurits

机构信息

1 Thomas Jefferson University Department of Otolaryngology-Head & Neck Surgery, Philadelphia, Pennsylvania, USA.

2 Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

出版信息

Ann Otol Rhinol Laryngol. 2017 Jun;126(6):478-482. doi: 10.1177/0003489417703408. Epub 2017 Apr 11.

DOI:10.1177/0003489417703408
PMID:28397553
Abstract

OBJECTIVE

Drug induced sleep endoscopy (DISE) allows for preoperative evaluation of the specific site and character of upper airway obstruction in obstructive sleep apnea (OSA). We aim to assess the impact DISE has on customizing the surgical plan and evaluate its role in surgical success.

METHODS

We retrospectively reviewed patients undergoing surgery for OSA. We compared those patients undergoing preoperative DISE to those that did not to assess procedures performed and surgical outcomes.

RESULTS

We found 87 patients undergoing surgery for OSA who had postoperative polysomnogram results. Of the group undergoing preoperative DISE, 8% had multilevel surgery. This compared to 59.5% in those not undergoing DISE ( p = .0004). The success rate of patients who had preoperative DISE was 86% compared to 51.4% in those who did not have preoperative DISE ( p < .001). We found no difference in age, gender, preoperative apnea-hypopnea index (AHI), oxygen nadir, Epworth sleepiness scale score (ESS), body mass index (BMI) and postoperative oxygen nadir, ESS, or BMI in the DISE and no DISE cohorts.

CONCLUSION

The addition of DISE to our preoperative workup has contributed to a decreased rate of multilevel surgery and increased rate of surgical success through identification of the individual patient's OSA architecture and customization of the surgical plan.

摘要

目的

药物诱导睡眠内镜检查(DISE)可用于术前评估阻塞性睡眠呼吸暂停(OSA)上气道阻塞的具体部位和特征。我们旨在评估DISE对制定手术方案的影响,并评估其在手术成功中的作用。

方法

我们回顾性分析了接受OSA手术的患者。我们比较了术前接受DISE的患者和未接受DISE的患者,以评估所实施的手术程序和手术结果。

结果

我们发现87例接受OSA手术的患者有术后多导睡眠图结果。在术前接受DISE的组中,8%进行了多级手术。相比之下,未接受DISE的组中这一比例为59.5%(p = .0004)。术前接受DISE的患者成功率为86%,而未接受术前DISE的患者成功率为51.4%(p < .001)。我们发现DISE组和未进行DISE组在年龄、性别、术前呼吸暂停低通气指数(AHI)、最低氧饱和度、爱泼华嗜睡量表评分(ESS)、体重指数(BMI)以及术后最低氧饱和度、ESS或BMI方面没有差异。

结论

在我们的术前检查中增加DISE,通过识别个体患者的OSA结构并定制手术方案,有助于降低多级手术的发生率并提高手术成功率。

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