Onkologische Praxis, Fuerth, Germany
Department of Radiotherapy and Radiation Oncology, Leopoldina Hospital Schweinfurt, Schweinfurt, Germany.
Oncologist. 2017 Apr;22(4):491. doi: 10.1634/theoncologist.2016-0402.
Diazoxide is a nondiuretic benzothiadiazine that produces hyperglycemia by lowering insulin levels through activation of ATP‐sensitive K1‐channels and stimulating insulin degradation in the lysosomal system. Its effect on cancer growth is discussed.
二氮嗪是一种非利尿苯并噻二嗪类药物，通过激活 ATP 敏感性 K + 通道降低胰岛素水平，并刺激溶酶体系统中胰岛素降解，从而导致高血糖。本文讨论了其对肿瘤生长的影响。
