Morsley Klara, Berntzen Berna, Erwood Lisa, Bellerby Toby, Williamson Lyn
Great Western Hospital, Swindon, UK.
Musculoskeletal Care. 2018 Mar;16(1):13-17. doi: 10.1002/msc.1193. Epub 2017 Apr 12.
Rheumatoid cachexia is common in rheumatoid arthritis (RA) patients and develops soon after diagnosis, despite adequate drug therapy. It is associated with multiple adverse effects on body composition, function and mortality. Progressive resistance training (PRT) improves these outcomes but is not widely prescribed outside of a research setting. The aim of the present study was to explore the practicality and effectiveness of providing PRT to patients in a district general hospital within the constraints of existing resources.
Patients attending a rheumatology clinic were invited to participate in a weekly PRT class for 6 weeks, supervised by a physiotherapist. Outcome measures included: body composition measures (waist and hip circumference, weight, percentage body fat); functional measures (grip strength, 60-s sit-to-stand test, single leg stance, Health Assessment Questionnaire); mood; fatigue and disease activity measures (sleep scale, hospital anxiety and depression scale, Functional Assessment of Chronic Illness Therapy, pain visual analogue scale). These were measured at baseline and at 6 weeks.
A total of 83 patients completed the programme (60% female, mean age 51.2 years), of whom 34.9% had early RA. Improvements were seen in multiple measures inpatients with early RA and with established inflammatory arthritis, and were not affected by age or gender.
Patients with early and established inflammatory arthritis alike benefited from a 6-week PRT programme provided within a National Health Service setting. Although further work is needed to look at long-term effects, we suggest that this intervention should be more widely available.
类风湿性恶病质在类风湿关节炎(RA)患者中很常见,尽管进行了充分的药物治疗,但在诊断后不久就会出现。它会对身体成分、功能和死亡率产生多种不良影响。渐进性抗阻训练(PRT)可改善这些结果,但在研究环境之外并未得到广泛应用。本研究的目的是在现有资源的限制下,探讨在地区综合医院为患者提供PRT的实用性和有效性。
邀请参加风湿病门诊的患者参加为期6周的每周一次的PRT课程,由物理治疗师监督。结果测量包括:身体成分测量(腰围和臀围、体重、体脂百分比);功能测量(握力、60秒坐立试验、单腿站立、健康评估问卷);情绪;疲劳和疾病活动测量(睡眠量表、医院焦虑抑郁量表、慢性病治疗功能评估、疼痛视觉模拟量表)。在基线和6周时进行测量。
共有83名患者完成了该项目(60%为女性,平均年龄51.2岁),其中34.9%患有早期RA。早期RA患者和已确诊的炎性关节炎患者在多项测量中均有改善,且不受年龄或性别的影响。
早期和已确诊的炎性关节炎患者都从国民医疗服务体系提供的为期6周的PRT项目中受益。尽管需要进一步研究长期效果,但我们建议这种干预措施应更广泛地提供。