Baldvinsdottir Bryndis, Hauksson Haraldur, Haraldsdóttir Kristin Huld
Laeknabladid. 2017 Apr;103(4):179-183. doi: 10.17992/lbl.2017.04.131.
Gallbladder carcinoma is about 0.5% of all cancer. The outcome of patients with gallbladder carcinoma is overall bad and the only potentially curative treatment is surgery. The aim of this study was to determine the disease's prevalence in Iceland and outcome of the patients diagnosed in the study period.
This was a retrospective study of all diagnosed patients with gallbladder carcinoma during the years 2004-2013. A list of patients was obtained from the Icelandic Cancer Registry. Information was gathered from the patient's charts in Landspitali University Hospital and the Hospital in Akureyri. Descriptive statistics was used to analyze the results. Median follow-up time was 6 years.
Twenty-four patients were diagnosed with gallbladder carci-noma in Iceland during the study period, 16 women and 8 men. Eighteen patients were diagnosed in Landspitali and six in the Hospital in Akureyri. The average age at diagnosis was 73 years. Eighteen patients have died, on average 5 months after the time of diagnosis. Adenocarcinoma was the most common cancer type (n=19). Three patients (3/24, 12.5%) underwent extended operation following the diagnosis of the gallbladder carcinoma. Nine patients (9/24, 37.5%) had advanced disease at the time of diagnosis and died within two months after being diagnosed with gallbladder carcinoma.
Gallbladder carcinoma is a rare cancer type in Iceland and has a bad prognosis. One third of the patients had no connection with Landspitali University Hospital following the diagnosis. Extended surgery following the diagnosis was seldom performed. Key words: gallbladder carcinoma, gastrointestinal cancer, adenocarcinoma, extended cholecystectomy. Correspondence: Kristin Huld Haraldsdottir, kristinh@landspitali.is.
胆囊癌约占所有癌症的0.5%。胆囊癌患者的总体预后较差，唯一可能治愈的治疗方法是手术。本研究的目的是确定该疾病在冰岛的患病率以及在研究期间确诊患者的预后情况。
这是一项对2004年至2013年间所有确诊的胆囊癌患者进行的回顾性研究。从冰岛癌症登记处获取患者名单。信息收集自冰岛国家大学医院和阿库雷里医院患者的病历。采用描述性统计分析结果。中位随访时间为6年。
在研究期间，冰岛有24例患者被诊断为胆囊癌，其中16例为女性，8例为男性。18例患者在冰岛国家大学医院被诊断，6例在阿库雷里医院被诊断。确诊时的平均年龄为73岁。18例患者已死亡，平均在确诊后5个月死亡。腺癌是最常见的癌症类型（n = 19）。3例患者（3/24，12.5%）在胆囊癌确诊后接受了扩大手术。9例患者（9/24，37.5%）在确诊时已患有晚期疾病，在被诊断为胆囊癌后两个月内死亡。
胆囊癌在冰岛是一种罕见的癌症类型，预后较差。三分之一的患者在确诊后与冰岛国家大学医院没有联系。确诊后很少进行扩大手术。关键词：胆囊癌、胃肠道癌、腺癌、扩大胆囊切除术。通信作者：克里斯汀·胡尔德·哈拉尔德斯多蒂尔，kristinh@landspitali.is 。
