• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

1 型神经纤维瘤病在多器官病损印加儿童干尸中的证据:使用计算机断层扫描的古放射学研究。

Evidence of neurofibromatosis type 1 in a multi-morbid Inca child mummy: A paleoradiological investigation using computed tomography.

机构信息

Department of Radiology, Trauma Center Murnau, Murnau, Germany.

Institute of Biomechanics, Trauma Center Murnau and Paracelsus Medical University Salzburg, Murnau, Germany.

出版信息

PLoS One. 2017 Apr 12;12(4):e0175000. doi: 10.1371/journal.pone.0175000. eCollection 2017.

DOI:10.1371/journal.pone.0175000
PMID:28403237
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5389647/
Abstract

OBJECTIVE

In this study, an Inca bundle was examined using computed tomography (CT). The primary aim was to determine the preservation status of bony and soft tissues, the sex, the age at the time of death, possible indicators for disease or even the cause of death, as well as the kind of mummification. A secondary aim was to obtain a brief overview of the wrapping in order to gain additional information on the cultural background.

MATERIALS AND METHODS

The bundle belongs to the Museum of Cultures in Basel, Switzerland, and was bought in Munich, Germany, in 1921. Radiocarbon dating of the superficial textile yielded a calibrated age between 1480 and 1650 AD. The mummy was investigated using multi-slice CT with slice thickness of 0.75 mm and 110 kilovolt. For standardized assessment of soft tissue preservation, a recently developed checklist was applied.

RESULTS

CT revealed the mummy of a seven to nine year old boy with superior preservation of bony and soft tissues allowing detailed assessment. Indicators of neurofibromatosis type 1 (paravertebral and cutaneous neurofibromas, a breast neurofibroma, sphenoid wing dysplasia), Chagas disease (dilatation of the esophagus, stomach, rectum, and large amounts of feces), and lung infection (pleural adherence, calcifications), probably due to tuberculosis, were found. Furthermore, signs of peri-mortem violence (transection of the chest and a defect in the abdominal wall) were detected. CT images revealed a carefully performed wrapping.

CONCLUSION

CT examination of the Inca bundle proved to be an important non-destructive examination method. Standardized assessment, especially of the soft tissue structures, allowed for diagnoses of several diseases, indicating a multi-morbid child at the time of death. The careful wrapping pointed to a ceremonial burial. Within the cultural background, the signs of fatal violence were discussed as a possible result of war, murder, accident, or human sacrifice.

摘要

目的

本研究使用计算机断层扫描(CT)检查了一个印加包裹。主要目的是确定骨骼和软组织的保存状况、性别、死亡时的年龄、可能的疾病指标,甚至死因,以及木乃伊的制作方式。次要目的是对包裹进行简要概述,以获取有关文化背景的更多信息。

材料和方法

包裹属于瑞士巴塞尔文化博物馆,于 1921 年在德国慕尼黑购买。对表面纺织品的放射性碳测年得出校准年龄在公元 1480 年至 1650 年之间。使用多层 CT 对木乃伊进行检查,层厚为 0.75 毫米,管电压为 110 千伏。为了标准化评估软组织保存情况,应用了最近开发的检查表。

结果

CT 显示了一个 7 至 9 岁男孩的木乃伊,骨骼和软组织保存完好,允许进行详细评估。发现了 1 型神经纤维瘤病(椎旁和皮肤神经纤维瘤、乳房神经纤维瘤、蝶骨翼发育不良)、恰加斯病(食管、胃、直肠扩张和大量粪便)和肺部感染(胸膜粘连、钙化)的指标,可能是由于结核病引起的。此外,还发现了生前暴力的迹象(胸部横断和腹壁缺损)。CT 图像显示了精心制作的包裹。

结论

对印加包裹的 CT 检查被证明是一种重要的非破坏性检查方法。对软组织结构的标准化评估,能够做出几种疾病的诊断,表明死亡时儿童患有多种疾病。精心的包裹表明这是一种仪式性的埋葬。在文化背景下,致命暴力的迹象被讨论为战争、谋杀、意外或人祭的可能结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb91/5389647/fd600f9d9223/pone.0175000.g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb91/5389647/68a424002673/pone.0175000.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb91/5389647/d39ea1f71934/pone.0175000.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb91/5389647/ef86a0703895/pone.0175000.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb91/5389647/e561b750aaea/pone.0175000.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb91/5389647/712e4188f166/pone.0175000.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb91/5389647/1b7fd0c832ce/pone.0175000.g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb91/5389647/8a0a85b799e7/pone.0175000.g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb91/5389647/08ee9a015bcb/pone.0175000.g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb91/5389647/fd600f9d9223/pone.0175000.g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb91/5389647/68a424002673/pone.0175000.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb91/5389647/d39ea1f71934/pone.0175000.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb91/5389647/ef86a0703895/pone.0175000.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb91/5389647/e561b750aaea/pone.0175000.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb91/5389647/712e4188f166/pone.0175000.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb91/5389647/1b7fd0c832ce/pone.0175000.g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb91/5389647/8a0a85b799e7/pone.0175000.g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb91/5389647/08ee9a015bcb/pone.0175000.g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb91/5389647/fd600f9d9223/pone.0175000.g009.jpg

相似文献

1
Evidence of neurofibromatosis type 1 in a multi-morbid Inca child mummy: A paleoradiological investigation using computed tomography.1 型神经纤维瘤病在多器官病损印加儿童干尸中的证据:使用计算机断层扫描的古放射学研究。
PLoS One. 2017 Apr 12;12(4):e0175000. doi: 10.1371/journal.pone.0175000. eCollection 2017.
2
From first to latest imaging technology: Revisiting the first mummy investigated with X-ray in 1896 by using dual-source computed tomography.从最早到最新的成像技术:利用双源计算机断层扫描重新审视1896年首例接受X射线检查的木乃伊。
Eur J Radiol Open. 2016 Jul 25;3:172-81. doi: 10.1016/j.ejro.2016.07.002. eCollection 2016.
3
Reconstructing the life of an unknown (ca. 500 years-old South American Inca) mummy--multidisciplinary study of a Peruvian Inca mummy suggests severe Chagas disease and ritual homicide.重建一具身份不明(约500年前的南美印加人)木乃伊的生平——对一具秘鲁印加木乃伊的多学科研究表明其患有严重的恰加斯病且死于仪式性杀人。
PLoS One. 2014 Feb 26;9(2):e89528. doi: 10.1371/journal.pone.0089528. eCollection 2014.
4
Checklist and Scoring System for the Assessment of Soft Tissue Preservation in CT Examinations of Human Mummies: Application to the Tyrolean Iceman.人类木乃伊CT检查中软组织保存评估的清单和评分系统:应用于蒂罗尔冰人
Rofo. 2017 Dec;189(12):1152-1160. doi: 10.1055/s-0043-116668. Epub 2017 Aug 23.
5
CT checklist and scoring system for the assessment of soft tissue preservation in human mummies: application to catacomb mummies from Palermo, Sicily.用于评估人类木乃伊软组织保存情况的CT检查清单和评分系统:应用于西西里岛巴勒莫的地下墓穴木乃伊
Int J Paleopathol. 2018 Mar;20:50-59. doi: 10.1016/j.ijpp.2018.01.003. Epub 2018 Feb 3.
6
Use of Computed Tomography scanning in a 'virtual' bioarchaeology of care analysis of a Central Coast Peruvian mummy bundle.计算机断层扫描在秘鲁中部海岸木乃伊包裹护理“虚拟”生物考古分析中的应用。
Int J Paleopathol. 2019 Jun;25:129-138. doi: 10.1016/j.ijpp.2018.12.006. Epub 2019 Feb 21.
7
Checklist and Scoring System for the Assessment of Soft Tissue Preservation in CT Examinations of Human Mummies.人类木乃伊CT检查中软组织保存评估的检查表和评分系统
PLoS One. 2015 Aug 5;10(8):e0133364. doi: 10.1371/journal.pone.0133364. eCollection 2015.
8
CT-Based Assessment of Relative Soft-Tissue Alteration in Different Types of Ancient Mummies.基于CT的不同类型古代木乃伊相对软组织变化评估
Anat Rec (Hoboken). 2015 Jun;298(6):1162-74. doi: 10.1002/ar.23144.
9
Scenes from the past: multidetector CT of Egyptian mummies of the Redpath Museum.过去的场景:雷德帕斯博物馆埃及木乃伊的多排 CT 扫描。
Radiographics. 2012 Jul-Aug;32(4):1235-50. doi: 10.1148/rg.324125704.
10
Medical imaging of mummies and bog bodies--a mini-review.古尸和泥炭鞣尸的医学成像——小型综述。
Gerontology. 2010;56(5):441-8. doi: 10.1159/000266031. Epub 2009 Dec 11.

引用本文的文献

1
Deep palaeoproteomic profiling of archaeological human brains.考古人类大脑的深度古蛋白质组学分析
PLoS One. 2025 May 28;20(5):e0324246. doi: 10.1371/journal.pone.0324246. eCollection 2025.
2
Pulsatile Proptosis and Sphenoid Wing Dysplasia with no Evidence of Neurofibromatosis Type 1: A Case Report and Review of the Literature.搏动性眼球突出伴蝶骨翼发育不良,无神经纤维瘤病 1 型证据:病例报告及文献复习。
Turk J Ophthalmol. 2024 Oct 25;54(5):304-308. doi: 10.4274/tjo.galenos.2024.10662.
3
Assessing Genotoxicity and Cytotoxicity Induced by X-Ray Exposure From Cone Beam Computed Tomography at Varied Fields of View.

本文引用的文献

1
Painting neurofibromatosis type 1 in the 15th century.
Lancet Neurol. 2016 Oct;15(11):1123. doi: 10.1016/S1474-4422(16)30210-1.
2
From first to latest imaging technology: Revisiting the first mummy investigated with X-ray in 1896 by using dual-source computed tomography.从最早到最新的成像技术:利用双源计算机断层扫描重新审视1896年首例接受X射线检查的木乃伊。
Eur J Radiol Open. 2016 Jul 25;3:172-81. doi: 10.1016/j.ejro.2016.07.002. eCollection 2016.
3
CT Scan of Thirteen Natural Mummies Dating Back to the XVI-XVIII Centuries: An Emerging Tool to Investigate Living Conditions and Diseases in History.对十三具可追溯至十六至十八世纪的天然木乃伊进行的CT扫描:一种用于研究历史上生活状况和疾病的新兴工具。
评估锥形束计算机断层扫描在不同视野下X射线照射所诱导的遗传毒性和细胞毒性。
Cureus. 2024 Aug 8;16(8):e66459. doi: 10.7759/cureus.66459. eCollection 2024 Aug.
PLoS One. 2016 Jun 29;11(6):e0154349. doi: 10.1371/journal.pone.0154349. eCollection 2016.
4
Frozen Mummies from Andean Mountaintop Shrines: Bioarchaeology and Ethnohistory of Inca Human Sacrifice.安第斯山顶神殿中的冰冻木乃伊:印加人殉葬的生物考古学与民族史
Biomed Res Int. 2015;2015:439428. doi: 10.1155/2015/439428. Epub 2015 Aug 6.
5
Checklist and Scoring System for the Assessment of Soft Tissue Preservation in CT Examinations of Human Mummies.人类木乃伊CT检查中软组织保存评估的检查表和评分系统
PLoS One. 2015 Aug 5;10(8):e0133364. doi: 10.1371/journal.pone.0133364. eCollection 2015.
6
Journal Club: Structured radiology reports are more complete and more effective than unstructured reports.期刊俱乐部:结构化的放射学报告比非结构化报告更完整、更有效。
AJR Am J Roentgenol. 2014 Dec;203(6):1265-71. doi: 10.2214/AJR.14.12636.
7
Structured reporting of multiphasic CT for pancreatic cancer: potential effect on staging and surgical planning.多期 CT 对胰腺癌的结构化报告:对分期和手术规划的潜在影响。
Radiology. 2015 Feb;274(2):464-72. doi: 10.1148/radiol.14140206. Epub 2014 Oct 3.
8
Pre-Columbian mycobacterial genomes reveal seals as a source of New World human tuberculosis.前哥伦布时期的分枝杆菌基因组揭示海豹是新大陆人类肺结核的一个来源。
Nature. 2014 Oct 23;514(7523):494-7. doi: 10.1038/nature13591. Epub 2014 Aug 20.
9
Evidence based palaeopathology: meta-analysis of Pubmed-listed scientific studies on pre-Columbian, South American mummies.循证古病理学:对PubMed列出的关于前哥伦布时期南美洲木乃伊的科学研究的荟萃分析。
Homo. 2014 Jun;65(3):214-31. doi: 10.1016/j.jchb.2014.03.001. Epub 2014 Mar 12.
10
Reconstructing the life of an unknown (ca. 500 years-old South American Inca) mummy--multidisciplinary study of a Peruvian Inca mummy suggests severe Chagas disease and ritual homicide.重建一具身份不明(约500年前的南美印加人)木乃伊的生平——对一具秘鲁印加木乃伊的多学科研究表明其患有严重的恰加斯病且死于仪式性杀人。
PLoS One. 2014 Feb 26;9(2):e89528. doi: 10.1371/journal.pone.0089528. eCollection 2014.