Feng Jian-Hua, Qian Yan
Department of Pediatric Hematology/Oncology, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2017 Apr;19(4):484-489. doi: 10.7499/j.issn.1008-8830.2017.04.023.
Neutrophils, an important type of human immune cells, are involved in host defense against infections. Neutropenia refers to a group of diseases manifesting as a reduction in the absolute value of mature neutrophils and is often accompanied by an increased risk of bacterial infection. According to etiology and pathogenesis, neutropenia is classified into congenital and acquired neutropenia. This article reviews the current research status and advances in the etiology of neutropenia in children. A deep understanding of the etiology of neutropenia helps to improve the diagnosis and treatment of this disease.
中性粒细胞是人体重要的免疫细胞类型，参与宿主对感染的防御。中性粒细胞减少症是一组表现为成熟中性粒细胞绝对值降低的疾病，常伴有细菌感染风险增加。根据病因和发病机制，中性粒细胞减少症可分为先天性和后天性中性粒细胞减少症。本文综述了儿童中性粒细胞减少症病因的研究现状与进展。深入了解中性粒细胞减少症的病因有助于改善该疾病的诊断和治疗。
