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经口内镜下甲状旁腺切除术(TOEPVA)治疗原发性甲状旁腺功能亢进症。

Primary hyperparathyroidism treated by transoral endoscopic parathyroidectomy vestibular approach (TOEPVA).

机构信息

Department of Surgery, Section of Endocrine Surgery, Yale University School of Medicine, 333 Cedar Street, FMB130A, Box 208062, New Haven, CT, 06520, USA.

出版信息

Surg Endosc. 2017 Nov;31(11):4832-4833. doi: 10.1007/s00464-017-5533-x. Epub 2017 Apr 13.

Abstract

BACKGROUND

Bilateral open cervical exploration with identifying all parathyroid glands and removing one or more enlarged parathyroid tumor(s) was the standard of care in primary hyperparathyroidism (pHPT). With the introduction of preoperative imaging and intraoperative parathyroid hormone (IOPTH) measurements [1, 2], various minimally invasive parathyroidectomy approaches have been developed, both open and endoscopic [3-8]. The most commonly used approach currently in the USA is the minimally invasive open parathyroidectomy (MIP), which can be performed in the ambulatory setting with excellent cure and minimal complication rates [9-12]. However, the operation requires a cervical incision, with occasionally poor cosmesis. The transoral endoscopic parathyroidectomy vestibular approach (TOEPVA) provides a novel "scarless" approach to parathyroid surgery.

METHODS

The aim of the video is to provide detailed instruction of the TOEPVA in pHPT and how to interpret IOPTH measurements in this setting.

RESULTS

The TOEPVA uses three incisions in the vestibule of the oral cavity, using two 5-mm ports and one central 11-mm port. The subplatysmal space is enlarged by hydrodissection and manual dilation. The working space is enhanced by insufflation to 6 mmHg. With the adjunct of preoperative imaging and IOPTH measurements, the extent of the operation is tailored to achieve biochemical cure.

CONCLUSIONS

TOEPVA is feasible and safe and provides an excellent cosmetic outcome. It is a more direct approach than other remote endoscopic parathyroidectomy techniques. TOEPVA is an excellent option for select patients with pHPT wishing to avoid a neck incision.

摘要

背景

双侧开放性颈探索,识别所有甲状旁腺腺体,并切除一个或多个增大的甲状旁腺肿瘤,是原发性甲状旁腺功能亢进症 (pHPT) 的标准治疗方法。随着术前影像学和术中甲状旁腺激素 (IOPTH) 测量的引入[1,2],各种微创甲状旁腺切除术方法已经发展起来,包括开放性和内镜性[3-8]。目前在美国最常用的方法是微创开放性甲状旁腺切除术 (MIP),它可以在门诊环境下进行,具有极好的治愈率和最小的并发症发生率[9-12]。然而,该手术需要进行颈部切口,偶尔会出现美容效果不佳的情况。经口内镜甲状旁腺切除术前庭入路 (TOEPVA) 为甲状旁腺手术提供了一种新颖的“无疤痕”方法。

方法

该视频旨在提供 pHPT 中 TOEPVA 的详细操作说明,以及如何在这种情况下解释 IOPTH 测量结果。

结果

TOEPVA 在口腔前庭使用三个切口,使用两个 5 毫米端口和一个中央 11 毫米端口。通过水分离和手动扩张扩大颈阔肌下空间。通过向手术空间内充气至 6 毫米汞柱来增强工作空间。结合术前影像学和 IOPTH 测量,手术范围可以根据需要进行调整,以达到生化治愈。

结论

TOEPVA 是可行且安全的,并且提供了极好的美容效果。与其他远程内镜甲状旁腺切除术技术相比,它是一种更直接的方法。对于希望避免颈部切口的选择 pHPT 患者,TOEPVA 是一个极好的选择。

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