特发性突发性听力损失小儿患者的中性粒细胞与淋巴细胞比值及血小板与淋巴细胞比值
Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Pediatric Patients with Idiopathic Sudden Hearing Loss.
作者信息
Bulğurcu Suphi, Dikilitaş Bünyamin, Arslan İlker Burak, Çukurova İbrahim
机构信息
Clinic of Otorhinolaryngology, Başkale State Hospital, Van, Turkey.
出版信息
J Int Adv Otol. 2017 Aug;13(2):217-220. doi: 10.5152/iao.2017.3404. Epub 2017 Apr 17.
OBJECTIVE
We investigated the significance of the neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios, which have recently been used in adults for the prognosis of idiopathic sudden hearing loss (ISHL), in the prognosis of idiopathic sudden hearing loss in a pediatric population.
MATERIALS AND METHODS
A total of 13 males and 8 females younger than19 years with idiopathic sudden hearing loss were retrospectively examined between January 2008 and August 2016.The control group consisted of 12 healthy males and 12 healthy females. Patients were divided into two groups: those who recovered after treatment and those who did not.
RESULTS
A statistical significance for the neutrophil-to-lymphocyte ratio was detected between the patient group and control group and between patients who recovered and those who did not (p<0.05). No statistical significance for the platelet-to-lymphocyte ratio was detected between the patient group and control group and between patients with recovery and those without recovery (p>0.05).
CONCLUSION
The neutrophil-to-lymphocyte ratio is an important marker for the prognosis of idiopathic sudden hearing loss in pediatric patients, similar to its use in adult patients.
目的
我们研究了中性粒细胞与淋巴细胞比值和血小板与淋巴细胞比值的意义，这两个比值最近在成人特发性突发性感音神经性听力损失（ISHL）的预后评估中得到应用，本研究旨在探讨它们在儿童特发性突发性感音神经性听力损失预后评估中的意义。
材料与方法
回顾性研究2008年1月至2016年8月期间13例男性和8例年龄小于19岁的女性特发性突发性感音神经性听力损失患者。对照组由12例健康男性和12例健康女性组成。患者分为两组：治疗后恢复的患者和未恢复的患者。
结果
患者组与对照组之间以及恢复患者与未恢复患者之间中性粒细胞与淋巴细胞比值存在统计学意义（p<0.05）。患者组与对照组之间以及恢复患者与未恢复患者之间血小板与淋巴细胞比值未检测到统计学意义（p>0.05）。
结论
中性粒细胞与淋巴细胞比值是儿童特发性突发性感音神经性听力损失预后的重要指标，这与它在成人患者中的应用类似。
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