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[Studies on biological damage by active oxygens. II. Inhibition of insulin release from isolated pancreatic islets by exposure to O2(-)-generating system of hypoxanthine-xanthine oxidase].

作者信息

Sakurai K, Ogawa Y, Miura T, Ogiso T

出版信息

Yakugaku Zasshi. 1988 Feb;108(2):150-5. doi: 10.1248/yakushi1947.108.2_150.

DOI:10.1248/yakushi1947.108.2_150
PMID:2841444
Abstract
摘要

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[Studies on biological damage by active oxygens. II. Inhibition of insulin release from isolated pancreatic islets by exposure to O2(-)-generating system of hypoxanthine-xanthine oxidase].[活性氧对生物的损伤研究。II. 次黄嘌呤-黄嘌呤氧化酶产O2(-)体系对离体胰岛胰岛素释放的抑制作用]
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Association of xanthine oxidoreductase inhibitor use with insulin secretory capacity in patients with type 2 diabetes.黄嘌呤氧化酶抑制剂的使用与 2 型糖尿病患者胰岛素分泌能力的关系。
J Diabetes Investig. 2024 Oct;15(10):1500-1509. doi: 10.1111/jdi.14279. Epub 2024 Jul 30.
2
Oxygen radicals generated by the enzyme xanthine oxidase lyse rat pancreatic islet cells in vitro.
Diabetologia. 1992 Nov;35(11):1028-34. doi: 10.1007/BF02221677.