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当质子泵抑制剂治疗无效时,我的患者仍有反流症状吗?

Does my patient still have reflux when ppi therapy does not work?

作者信息

Vaezi M F

机构信息

Professor of Medicine and Clinical Director, Division of Gastroenterology and Hepatology, Director Center for Swallowing and Esophageal Disorders, Director Clinical Research, Vanderbilt University Medical Center, Nashville, TN, USA.

出版信息

Neurogastroenterol Motil. 2017 May;29(5). doi: 10.1111/nmo.13065.

DOI:10.1111/nmo.13065
PMID:28414898
Abstract

Gastroesophageal reflux disease (GERD) is a common condition around the world. The management of this disease is less than satisfying given complexity of patient presentation and suboptimal diagnostic testing when employed for those poorly responsive to acid suppressive therapy. In this mini review, we discuss some new strategies employed for patients with suspected GERD to better understand disease pathophysiology. We compare the strategies and outline a clinically relevant approach in this difficult group of patients.

摘要

胃食管反流病(GERD)在全球范围内是一种常见疾病。鉴于患者表现的复杂性以及用于对抑酸治疗反应不佳者的诊断测试不理想,该疾病的管理并不令人满意。在这篇小型综述中,我们讨论了用于疑似GERD患者的一些新策略,以更好地理解疾病的病理生理学。我们比较了这些策略,并为这一困难患者群体概述了一种临床相关方法。

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