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Accidental intrathecal administration of vincristine.

作者信息

Shepherd D A, Steuber C P, Starling K A, Fernbach D J

出版信息

Med Pediatr Oncol. 1978;5(1):85-8. doi: 10.1002/mpo.2950050113.

DOI:10.1002/mpo.2950050113
PMID:284172
Abstract

Vincristine is a chemotherapeutic agent used in the treatment of various neoplastic diseases. Its neurotoxicity after therapeutic and pharmacologic doses has been well documented. We report a case of accidental intrathecal administration of vincristine in order to describe the complications seen, discuss possible means of therapeutic intervention, and serve as a reminder that preventive measures are mandatory to avoid such accidents in the future.

摘要

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