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一名由反向银屑病引发的脓疱型银屑病病程迁延患者对单剂量英夫利昔单抗产生显著反应。

A dramatic response to a single dose of infliximab in a patient with prolonged pustular psoriasis derived from inverse psoriasis.

作者信息

Li Mengmeng, Dai Weiwei, Yan Wei, Liu Yuanzhen, Wang Lian, Li Wei

机构信息

Department of Dermatovenereology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.

Department of Dermatovenereology, Chengdu University of Traditional Chinese Medicine Hospital, Chengdu, Sichuan, China.

出版信息

Dermatol Ther. 2017 Jul;30(4). doi: 10.1111/dth.12492. Epub 2017 Apr 17.

Abstract

We report a case of a 25-year-old Chinese man with an exceptionally prolonged history of pustular psoriasis derived from inverse psoriasis who was unsatisfied with conventional treatment and was successfully treated with a single dose of infliximab without noticeable adverse effects. No recurrence or flaring was observed after 3 months of follow-up. This case illustrates that infliximab may be an effective and safe therapeutic option for patients with refractory pustular psoriasis derived from inverse psoriasis.

摘要

我们报告了一例25岁的中国男性病例,该患者因反向银屑病引发脓疱型银屑病,病程异常漫长,对传统治疗不满意,经单剂量英夫利昔单抗成功治疗,且无明显不良反应。随访3个月后未观察到复发或病情加重。该病例表明,英夫利昔单抗可能是治疗反向银屑病所致难治性脓疱型银屑病患者的一种有效且安全的治疗选择。

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