Infectious Diseases Department, National Institute of Health Dr. Ricardo Jorge, URSZ, Lisbon, Portugal.
Scientific Area of Mathematics, Lisbon School of Health Technology, Polytechnic Institute of Lisbon, Lisbon, Portugal.
Mycopathologia. 2017 Oct;182(9-10):863-867. doi: 10.1007/s11046-017-0133-9. Epub 2017 Apr 18.
Candida albicans is a common microbe, colonizer and potential pathogen found in respiratory cultures of cystic fibrosis (CF) patients. Because of possible development of resistance in patient isolates resulting from residence in the abnormal milieu of CF patient airways, or from exposure to antifungals, and considering the possibility of patient-to-patient spread of microbes and reports of elevated resistance to other fungal pathogens, it was important to assay the susceptibility of isolates of Candida and compare that profile to isolates from the community. In our center, and unlike another fungal pathogen, no increase in resistance of Candida isolates of the CF cohort was found.
白色念珠菌是一种常见的微生物,定植于囊性纤维化(CF)患者的呼吸道,可能成为潜在的病原体。由于 CF 患者气道的异常环境,或由于接触抗真菌药物,患者分离株可能产生耐药性,并且考虑到微生物在患者间传播的可能性,以及对其他真菌病原体耐药性升高的报道,检测分离株的药敏性并将其与社区分离株进行比较很重要。在我们中心,与另一种真菌病原体不同,CF 队列的白色念珠菌分离株没有发现耐药性增加。