Trindade Aline Heloísa, Meira Henrique Côrtes, Pereira Igor Figueiredo, de Lacerda Julio César Tanos, de Mesquita Ricardo Alves, Santos Vagner Rodrigues
Department of Clinical Pathology and Surgery, School of Dentistry, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.
Department of Dentistry, University center Newton Paiva, Belo Horizonte, MG, Brazil.
Mycoses. 2017 Aug;60(8):521-525. doi: 10.1111/myc.12622. Epub 2017 Apr 19.
Paracoccidioidomycosis (PCM) is a rare fungal infection in the world, but endemic and acquired exclusively in Latin America, with the highest prevalence in South America and Brazil, particularly. Changes in oral cavity are common and constitute the first clinical manifestation in many patients. The aim of this study was to describe the prevalence of oral PCM and analyse the profile of the disease and patients. Retrospective research, consisting of information present in the medical records in the period 1998-2015, whose histopathological diagnosis was oral PCM. Fifty-five oral PCM cases were confirmed. Of these patients, 90.9% were males and 9.1% were females. The average age was 49.66 years and the most reported occupation was rural workers. The painful symptomatology was present in 61.82% of patients. Erythematous lesions were predominant in 73% of them. In single lesions (22 cases), the most common locations were jugal mucosa and tongue. In multiple involvement (30 cases), the most affected regions were lips, jugal mucosa and alveolar ridge. Epidemiology of PCM, was similar to several other studies, especially in Brazil. This is the most important fungal infection in Latin America and the recognition of oral lesions is extremely important, as is often the first and in many cases the only manifestation of the disease.
副球孢子菌病（PCM）是一种在全球范围内罕见的真菌感染，但仅在拉丁美洲流行且为人所感染，在南美洲尤其是巴西的患病率最高。口腔病变很常见，是许多患者的首发临床表现。本研究旨在描述口腔PCM的患病率，并分析该病及患者的特征。采用回顾性研究，收集1998 - 2015年期间病历中的信息，其组织病理学诊断为口腔PCM。确诊55例口腔PCM病例。其中，男性患者占90.9%，女性患者占9.1%。平均年龄为49.66岁，报告最多的职业是农民工。61.82%的患者有疼痛症状。73%的患者以红斑性病变为主。在单发病变（22例）中，最常见的部位是颊黏膜和舌。在多发受累（30例）中，受影响最严重的区域是嘴唇、颊黏膜和牙槽嵴。PCM的流行病学情况与其他几项研究相似，尤其是在巴西。这是拉丁美洲最重要的真菌感染，认识口腔病变极其重要，因为它往往是该病的首发症状，且在许多情况下是唯一的表现。
