Bootz F, Helliwell T R, Gärtner H V
HNO-Klinik der Universität Tübingen.
HNO. 1988 Apr;36(4):166-70.
We report two cases of chemodectoma of the larynx. A 70-year-old man underwent a laryngectomy in April 1984 for a tumor diagnosed as a squamous cell carcinoma but which postoperatively proved to be a chemodectoma. Ipsilateral cervical metastases appeared 2 years later and were removed by local excision. Shortly thereafter he presented with recurrent nodes in both sides of the neck as well as cutaneous metastases on the trunk. He was given chemotherapy using a DTIC regime (5-3,3-dimethyl-1-triazino imidazole-4-carboxamide). A 53-year-old lady underwent a total laryngectomy in May 1984 for an extensive chemodectoma of the larynx. The tumor had already invaded the trachea and thyroid gland. Distant metastases were not found. So far she is free of recurrence. We discuss the histology, site, clinical course and therapy of this extremely rare tumor.
我们报告两例喉化学感受器瘤。一名70岁男性于1984年4月因被诊断为鳞状细胞癌而接受了喉切除术,但术后病理证实为化学感受器瘤。两年后出现同侧颈部转移,通过局部切除进行了清除。此后不久,他双侧颈部出现复发淋巴结以及躯干皮肤转移。他接受了使用达卡巴嗪方案(5-3,3-二甲基-1-三嗪咪唑-4-甲酰胺)的化疗。一名53岁女性于1984年5月因广泛的喉化学感受器瘤接受了全喉切除术。肿瘤已侵犯气管和甲状腺。未发现远处转移。到目前为止,她没有复发。我们讨论了这种极其罕见肿瘤的组织学、部位、临床过程及治疗方法。