Van Roĭen E A, Van Oerle M S, Griĭn R
Med Radiol (Mosk). 1988 Aug;33(8):58-61.
Focal nodular liver hyperplasia (FNLH) is a benign liver tumor developing mostly in young women but occurring sometimes in men. It is often confused with other liver diseases, particularly with hepatic cell adenoma. Differential diagnosis of these diseases is very important because their prognosis and therapy are quite different. The presence of functioning Kupffer cell determined by scintigraphy with 99mTc-colloid is a decisive factor in FNLH diagnosis. However colloid accumulation was not recorded in 30-50% of patients (according to literature data), and there were cold zones on scans. 99mTc-colloid uptake can be determined by single-photon emission computed tomography.
局灶性结节性肝增生(FNLH)是一种主要发生于年轻女性,但有时也见于男性的良性肝脏肿瘤。它常与其他肝脏疾病相混淆,尤其是肝细胞腺瘤。对这些疾病进行鉴别诊断非常重要,因为它们的预后和治疗方法有很大差异。通过99mTc胶体闪烁扫描术确定的功能性库普弗细胞的存在是FNLH诊断的决定性因素。然而,根据文献数据,30%-50%的患者未记录到胶体聚集,扫描时有冷区。99mTc胶体摄取可通过单光子发射计算机断层扫描来确定。