[Roentgen morphology of bone metastases of breast cancer as affected by antineoplastic therapy].

The changes in bone metastases from carcinoma of the breast induced by treatment have been analysed from their radiological appearances in a series of 58 patients and for an average period of 7.2 years. Indicators of regression are recalcification or re-ossification of primary osteolyses (46.8%), the development of marginal sclerosis round the defect (15.9%) and lack of progression over a period of 9 to 12 months (11.6%). Decreased sclerosis in primary osteosclerotic metastases (9.4%) may also be evidence of regression. Primary osteolytic/osteosclerotic metastases behave similar as osteolytic lesions. Recurrence or progress of tumour produces new metastases (39.6%), progressive osteolysis (26.6%), sclerosis (7.3%) and increased tumour size (15.4%).