Appuhamy Chinthaka, Kwan Justin, H'ng Martin Weng Chin, Narayanan Sriram, Punamiya Sundeep
Department of Diagnostic Radiology, Tan Tock Seng Hospital, Singapore.
Department of Vascular Surgery, Tan Tock Seng Hospital, Singapore.
Singapore Med J. 2017 Apr;58(4):184-188. doi: 10.11622/smedj.2017028.
A 52-year-old man, who had a background of chronic heart disease and atrial fibrillation, as well as non-compliance with warfarin therapy, presented with a two-week history of worsening upper abdominal pain. Computed tomography mesenteric angiography showed complete embolic occlusion of the coeliac artery with resultant segmental splenic infarction, and thrombus within the left ventricle. A decision was made to proceed with catheter-directed thrombolysis. Subsequent follow-up angiogram at 12 hours showed successful treatment with complete dissolution of the coeliac embolus. The patient's symptoms resolved during his hospitalisation and he was subsequently discharged well on long-term oral anticoagulation therapy. Isolated acute embolic occlusion of the coeliac axis is a rare occurrence that may result in end-organ infarction. Treatment options include systemic anti-coagulation, mechanical thrombectomy, catheter thrombolysis or open surgery. Catheter-directed thrombolysis therapy is a feasible and effective option for treating acute thromboembolic occlusion of the coeliac artery.
一名52岁男性,有慢性心脏病和心房颤动病史,且未遵医嘱服用华法林治疗,出现上腹部疼痛加重两周的症状。计算机断层扫描肠系膜血管造影显示腹腔干完全栓塞性闭塞,导致节段性脾梗死,左心室内有血栓。决定进行导管定向溶栓治疗。随后在12小时进行的随访血管造影显示治疗成功,腹腔干栓子完全溶解。患者的症状在住院期间得到缓解,随后出院,接受长期口服抗凝治疗。孤立性腹腔干急性栓塞性闭塞是一种罕见的情况,可能导致终末器官梗死。治疗选择包括全身抗凝、机械取栓、导管溶栓或开放手术。导管定向溶栓治疗是治疗腹腔干急性血栓栓塞性闭塞的一种可行且有效的选择。