College of Materials, Chemistry and Chemical Engineering, Hangzhou Normal University , Hangzhou 310036, China.
J Org Chem. 2017 May 19;82(10):5222-5229. doi: 10.1021/acs.joc.7b00480. Epub 2017 Apr 27.
A catalytic oxidative cyclization of 2-aminopyridines or 2-aminobenzothiazole with 2-phenoxyacetophenones (a kind of lignin platform compound) was developed, efficiently providing valuable 3-phenoxy imidazo[1,2-a]pyridines or 3-phenoxy benzo[d]imidazo[2,1-b]thiazoles. The reaction was realized under oxygen by simply using inexpensive CuI as the catalyst.
开发了一种 2-氨基吡啶或 2-氨基苯并噻唑与 2-苯氧基苯乙酮（一种木质素平台化合物）的催化氧化环化反应，有效地提供了有价值的 3-苯氧基咪唑并[1,2-a]吡啶或 3-苯氧基苯并[d]咪唑并[2,1-b]噻唑。该反应在氧气下简单地使用廉价的 CuI 作为催化剂即可实现。
