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输尿管支架硬式输尿管镜与软式膀胱镜取出术的前瞻性随机对照研究。

A prospective and randomized comparison of rigid ureteroscopic to flexible cystoscopic retrieval of ureteral stents.

作者信息

Lai Dehui, Chen Meiling, Zha Shifang, Wan Shawpong

机构信息

Urology Department, Fifth Affiliated Hospital, Guangzhou Medical University, 621 Gangwan Road, Huangpu District, Guangzhou, 510700, China.

Urology, Citic Huizhou Hospital, Huizhou, Guangdong, China.

出版信息

BMC Urol. 2017 Apr 21;17(1):31. doi: 10.1186/s12894-017-0220-8.

Abstract

BACKGROUND

Flexible cystoscopy has become an accepted alternative for stent retrieval. However, it is associated with higher cost. Some reports have described experiences of using rigid ureteroscope to retrieve ureteral stents. We compared rigid ureteroscopic to flexible cystoscopic retrieval of ureteral stents in a prospective and randomized clinical trial.

METHODS

Three hundred patients treated with ureteral stents between July 2012 and July 2013 were accrued in this study. These patients were divided into two groups using the random number table method. Group A, with 162 patients, had stents removed with a flexible cystoscope and Group B, with 138 patients, had stents removed with a rigid ureteroscope. All procedures were performed under topical anesthesia by the same urologist. Patients in each group were compared in terms of preoperative, perioperative, and postoperative data. Postoperative data were collected using telephone interview on the postoperative day two. The postoperative questionnaire used included three items: hematuria, irritable bladder symptoms, and pain scores.

RESULTS

All the stents were retrieved successfully. No statistical differences were noted between the two groups in terms of gender, age, laterality and duration of the stents, operative time, postoperative hematuria, irritable bladder symptoms, and pain scores. The per-use cost of instrument was much higher for the flexible cystoscopic group, RMB 723.1 versus 214.3 (USD 107.9 versus 28.2), P < 0.05.

CONCLUSION

Ureteral stent retrieval using rigid ureteroscope under topical anesthesia is as safe and effective as flexible cystoscope but with a much lower cost to patients.

TRIAL REGISTRATION

This study was registered with Chinese Clinical Trial Registry on March 27, 2017 (retrospective registration) with a trial registration number of ChiCTR-IOR-17010986 .

摘要

背景

软性膀胱镜检查已成为取出支架的一种公认替代方法。然而,其成本较高。一些报告描述了使用硬性输尿管镜取出输尿管支架的经验。我们在一项前瞻性随机临床试验中比较了硬性输尿管镜与软性膀胱镜取出输尿管支架的情况。

方法

2012年7月至2013年7月期间接受输尿管支架治疗的300例患者纳入本研究。采用随机数字表法将这些患者分为两组。A组162例患者,用软性膀胱镜取出支架;B组138例患者,用硬性输尿管镜取出支架。所有手术均由同一位泌尿外科医生在局部麻醉下进行。比较两组患者术前、围手术期和术后的数据。术后第2天通过电话访谈收集术后数据。术后问卷包括三项内容:血尿、膀胱刺激症状和疼痛评分。

结果

所有支架均成功取出。两组在性别、年龄、支架放置侧别和时间、手术时间、术后血尿、膀胱刺激症状和疼痛评分方面均无统计学差异。软性膀胱镜组器械单次使用成本远高于硬性输尿管镜组,分别为723.1元对214.3元(107.9美元对28.2美元),P<0.05。

结论

在局部麻醉下使用硬性输尿管镜取出输尿管支架与软性膀胱镜一样安全有效,但患者成本低得多。

试验注册

本研究于2017年3月27日在中国临床试验注册中心注册(回顾性注册),试验注册号为ChiCTR-IOR-17010986。

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