Zhan Jia, Diao Xue-Hong, Chen Lin, Jin Jia-Mei, Chen Yue
Department of Ultrasound, Huadong Hospital, Fudan University, Shanghai, China.
Department of Ultrasound, Huadong Hospital, Fudan University, Shanghai, China.
Ultrasound Med Biol. 2017 Jun;43(6):1179-1186. doi: 10.1016/j.ultrasmedbio.2017.02.006. Epub 2017 Apr 19.
The aim of this study was to evaluate the clinical value of contrast-enhanced ultrasound (CEUS) in the diagnosis of thyroid nodules in the acoustic radiation force impulse (ARFI) "gray zone" (the shear wave velocity is in the range 2.5-3 m/s). ARFI was performed before thyroidectomy in 70 patients with 200 thyroid nodules, and then CEUS was performed in 40 thyroid nodules in the "gray zone." The accuracy of ARFI for the 200 thyroid nodules was 82% (164/200). The accuracy of ARFI for the 40 "gray zone" thyroid nodules was 70% (28/40), whereas the accuracy of CEUS for the "gray zone" thyroid nodules was 90% (36/40). There was a significant difference in accuracy (p < 0.05). CEUS has better accuracy for thyroid nodules in the ARFI "gray zone." CEUS supplemented ARFI in differential diagnosis of benign and malignant thyroid nodules.
本研究旨在评估超声造影（CEUS）在诊断处于声辐射力脉冲（ARFI）“灰色区域”（剪切波速度范围为2.5 - 3 m/s）的甲状腺结节中的临床价值。对70例患有200个甲状腺结节的患者在甲状腺切除术前进行ARFI检查，然后对40个处于“灰色区域”的甲状腺结节进行CEUS检查。200个甲状腺结节的ARFI诊断准确率为82%（164/200）。40个“灰色区域”甲状腺结节的ARFI诊断准确率为70%（28/40），而CEUS对“灰色区域”甲状腺结节的诊断准确率为90%（36/40）。准确率存在显著差异（p < 0.05）。CEUS对ARFI“灰色区域”的甲状腺结节具有更高的诊断准确率。在甲状腺结节良恶性的鉴别诊断中，CEUS补充了ARFI的诊断价值。
