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个人视角:我与约翰·肯德鲁的四次相遇

A Personal Perspective: My Four Encounters with John Kendrew.

机构信息

Department of Cell, Developmental, and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

出版信息

J Mol Biol. 2017 Aug 18;429(17):2594-2600. doi: 10.1016/j.jmb.2017.04.010. Epub 2017 Apr 20.

Abstract

By celebrating the 100th anniversary of John Kendrew's birth in 1917, the Journal of Molecular Biology recognizes his seminal contributions to science in general and structural biology in particular. John was first to use X-ray diffraction to solve the 3-dimensional structure of a protein, sperm-whale myoglobin, worthy of a Nobel Prize in Chemistry in 1962. John was the Founder and first Editor-in-Chief of the Journal of Molecular Biology, Deputy Chairman of the Laboratory of Molecular Biology and Head of its Division of Structural Studies, a Founder of the European Molecular Biology Organization, first Director-General of the European Molecular Biology Laboratory, and 33rd President of St. John's College, Oxford. In this personal perspective I relate how I came to know John as his postdoctoral fellow at the Laboratory of Molecular Biology in 1967 and as his biographer 45 years later.

摘要

通过庆祝约翰·肯德鲁(John Kendrew)于 1917 年诞生 100 周年,《分子生物学杂志》(Journal of Molecular Biology)向他在科学,特别是结构生物学方面的开创性贡献致敬。约翰是首位使用 X 射线衍射技术解决蛋白质——抹香鲸肌红蛋白的三维结构的人,这一成就值得在 1962 年获得诺贝尔化学奖。他是《分子生物学杂志》(Journal of Molecular Biology)的创始人和首任主编、分子生物学实验室的副主席、结构研究部主任、欧洲分子生物学组织的创始人之一、欧洲分子生物学实验室的首任总干事、牛津大学圣约翰学院的第 33 任院长。在这篇个人视角的文章中,我讲述了自己是如何在 1967 年作为他在分子生物学实验室的博士后研究员,以及 45 年后作为他的传记作者与他相识的。

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