Chan P J, Henig I, Tredway D R
Department of Obstetrics and Gynecology, Oral Roberts University School of Medicine, Tulsa, Oklahoma 74104.
Experientia. 1988 Sep 15;44(9):774-5. doi: 10.1007/BF01959161.
The dibutyryl analog of cCMP enlarged the nuclei of trophoblast giant cells and promoted blastocyst development. The result suggests that cCMP has a trophic effect on embryonic development, specifically by altering the size of the trophoblast cell nucleus but does not enhance trophoblast cell proliferation processes.