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哥伦比亚卡利市Fundacion Valle del Lili医院肾移植和骨髓移植受者中多瘤病毒BK(BKV)及新出现的非洲变种的流行病学

Epidemiology of polyomavirus BK (BKV) and the emergent African variant in kidney and bone marrow transplant recipients in the Fundacion Valle del Lili in Cali, Colombia.

作者信息

Ocampo Luz Ángela, Rosso Fernando, Pacheco Robinson, Villegas Adriana

机构信息

Pathology Department and Laboratory Medicine, Immunology Laboratory of Transplants and Immunogenetics, Fundación Valle del Lili, Cali, Colombia.

Department of Internal Medicine and Infectology, Fundación Valle del Lili, Cali, Colombia; Department of Public Health, Faculty of Health, Universidad ICESI, Cali, Colombia.

出版信息

Diagn Microbiol Infect Dis. 2017 Jul;88(3):236-240. doi: 10.1016/j.diagmicrobio.2017.01.025. Epub 2017 Apr 6.

DOI:10.1016/j.diagmicrobio.2017.01.025
PMID:28434897
Abstract

To describe the epidemiology of BKV and to assess the presence of the African variant in bone marrow and kidney transplant patients who have suspected BKV reactivation. A descriptive study was conducted, using institutional records, at the Fundación Valle del Lili, Cali-Colombia. The overall prevalence of BKV during the study period was 51%. The African variant was identified in 49.4% of samples that were positive for BKV. 50.6% of the samples were found to have the wild strain of BKV. Among BKV positive patients, 57% were kidney transplant recipients and 43% were bone marrow transplant recipients. This is the first epidemiological study describing the African variant of BKV in Colombia.

摘要

描述BK病毒的流行病学特征,并评估疑似BK病毒再激活的骨髓和肾移植患者中非洲变种的存在情况。在哥伦比亚卡利市的瓦莱德尔利利基金会,利用机构记录进行了一项描述性研究。研究期间BK病毒的总体患病率为51%。在BK病毒检测呈阳性的样本中,49.4%鉴定出非洲变种。50.6%的样本被发现含有BK病毒野生株。在BK病毒阳性患者中,57%是肾移植受者,43%是骨髓移植受者。这是哥伦比亚第一项描述BK病毒非洲变种的流行病学研究。

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