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近红外光谱技术在中药质量控制与过程监测中的应用进展

[Application progress on near infrared spectroscopy in quality control and process monitoring of traditional Chinese medicine].

作者信息

Li Wenlong, Qu Haibin

机构信息

Pharmaceutical Informatics Institute, Zhejiang University, Hangzhou 310058, China.

出版信息

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2017 Jan 25;46(1):80-88. doi: 10.3785/j.issn.1008-9292.2017.02.12.

Abstract

The industry of traditional Chinese medicine (TCM) encounters problems like quality fluctuation of raw materials and unstandardized production process. Near infrared (NIR) spectroscopy technology is widely used in quality control of TCM because of its abundant information, fast and nondestructive characters. The main applications include quantitative analysis of Chinese medicinal materials, intermediates and Chinese patent medicines; the authenticity of TCM, species, origins and manufacturers; monitoring and control of the extraction, alcohol precipitation, column chromatography and blending process. This article reviews the progress on the application of NIR spectroscopy technology in TCM field. In view of the problems existing in the application, the article proposes that the standardization of NIR analysis method should be developed according to specific characteristics of TCM, which will promote the application of NIR technology in the TCM industry.

摘要

中医药行业面临着原材料质量波动和生产过程不规范等问题。近红外(NIR)光谱技术因其信息丰富、快速且无损的特点,在中药质量控制中得到广泛应用。其主要应用包括中药材、中间体和中成药的定量分析;中药的真伪、品种、产地和生产厂家鉴别;提取、醇沉、柱色谱和混合过程的监测与控制。本文综述了近红外光谱技术在中药领域应用的进展。针对应用中存在的问题,文章提出应根据中药的具体特性制定近红外分析方法的标准化,这将推动近红外技术在中药行业的应用。

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