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比较采用髓内固定治疗的开放性和闭合性胫骨骨折的医院治疗效果。

Comparing hospital outcomes between open and closed tibia fractures treated with intramedullary fixation.

作者信息

Smith Evan J, Kuang Xiangyu, Pandarinath Rajeev

机构信息

The George Washington University Department of Orthopedics.

The Milken Institute School of Public Health.

出版信息

Injury. 2017 Jul;48(7):1609-1612. doi: 10.1016/j.injury.2017.03.038. Epub 2017 Mar 30.

Abstract

INTRODUCTION

Tibial shaft fractures comprise a large portion of operatively treated long bone fractures, and present with the highest rate of open injuries. Intramedullary fixation has become the standard of care for both open and closed injuries. The rates of short term complications and hospital length of stay for open and closed fractures treated with intramedullary fixation is not fully known. Previous series on tibia fractures were performed at high volume centers, and data were not generalizable, further they did not report on length of stay and the impact of preoperative variables on infections, complications and reoperation. We used a large surgical database to compare these outcomes while adjusting for preoperative risk factors.

METHODS

Data were extracted from the ACS-NSQIP database from 2005 to 2014. Cases were identified based on CPT codes for intramedullary fixation and categorized as closed vs open based on ICD9 code. In addition to demographic and case data, primary analysis examined correlation between open and closed fracture status with infection, complications, reoperation and hospital length of stay. Secondary analysis examined preoperative variables including gender, race, age, BMI, and diabetes effect on outcomes.

RESULTS

There were 272 cases identified. There were no significant demographic differences between open and closed tibia fracture cases. Open fracture status did not increase the rate of infection, 30day complications, reoperation, or length of stay. The only preoperative factor that correlated with length of stay was age. There was no correlation between BMI, presence of insulin dependent and nondependent diabetes, and any outcome measure.

DISCUSSION

When considering the complication rates for open and closed tibial shaft fractures treated with intramedullary fixation, there is no difference between 30-day complication rate, length of stay, or return to the operating room. Our reported postoperative infection rates were comparable to previous series, adding validity to our results. The heterogeneity of the hospitals included in ACS-NSQIP database allow our data to be generalizable. These methods may underrepresent the true occurrence of infection as operatively treated tibia infections may present late, requiring late revision. Despite limitations, the data reflect on the current burden of managing these once devastating injuries.

摘要

引言

胫骨干骨折占手术治疗长骨骨折的很大一部分,且开放性损伤发生率最高。髓内固定已成为开放性和闭合性损伤的标准治疗方法。采用髓内固定治疗开放性和闭合性骨折的短期并发症发生率及住院时间尚不完全清楚。以往关于胫骨骨折的系列研究是在高容量中心进行的,数据缺乏普遍性,而且他们没有报告住院时间以及术前变量对感染、并发症和再次手术的影响。我们使用一个大型手术数据库来比较这些结果,同时对术前风险因素进行调整。

方法

数据取自2005年至2014年的美国外科医师学会国家外科质量改进计划(ACS-NSQIP)数据库。根据髓内固定的现行程序编码(CPT)识别病例,并根据国际疾病分类第九版(ICD9)编码将其分为闭合性骨折与开放性骨折。除人口统计学和病例数据外,主要分析研究开放性和闭合性骨折状态与感染、并发症、再次手术及住院时间之间的相关性。次要分析研究术前变量,包括性别、种族、年龄、体重指数(BMI)和糖尿病对结果的影响。

结果

共识别出272例病例。开放性和闭合性胫骨干骨折病例在人口统计学上无显著差异。开放性骨折状态并未增加感染率、30天并发症发生率、再次手术率或住院时间。与住院时间相关的唯一术前因素是年龄。BMI、胰岛素依赖型和非胰岛素依赖型糖尿病的存在与任何结果指标之间均无相关性。

讨论

在考虑采用髓内固定治疗开放性和闭合性胫骨干骨折的并发症发生率时,30天并发症发生率、住院时间或再次手术率并无差异。我们报告的术后感染率与以往系列研究相当,这为我们的结果增添了可信度。ACS-NSQIP数据库中纳入的医院具有异质性,使我们的数据具有普遍性。这些方法可能无法充分代表感染的实际发生率,因为手术治疗的胫骨感染可能出现较晚,需要后期翻修。尽管存在局限性,但这些数据反映了当前处理这些曾经具有毁灭性损伤的负担。

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