Mologne Mitchell S, Quan Theodore, Mikula Jacob D, Garcia Alexander R, Best Matthew J, Thakkar Savyasachi C
Washington University School of Medicine, St. Louis, MO, USA.
George Washington School of Medicine and Health Sciences, Washington, DC, USA.
Arch Bone Jt Surg. 2024;12(9):637-644. doi: 10.22038/ABJS.2024.75059.3470.
This study was conducted to determine if factors comprising the mFI were correlated with adverse outcomes following surgical intervention of tibial shaft fractures.
We identified patients 50 years or older with tibial shaft fractures that were managed surgically from a national database from 2007-2019. The 5-item mFI score, which comprised of diabetes, hypertension, congestive heart failure, dependent functional status, and chronic obstructive pulmonary disease, was calculated for each patient. Regression analysis was used to evaluate the association of different mFI scores with thirty-day postoperative outcomes.
1,159 total patients (mean age of 65 years) were included in this study. After controlling for confounding variables on multivariate analysis, compared to patients with a mFI of 0, those with a score of 1 had an increased risk of major complications (OR 5.11; p=0.038), minor complications (OR 3.11; p=0.004), readmission (OR 2.75; p=0.020), postoperative transfusion (OR 2.22; p=0.037), prolonged hospital stay (OR 1.88; p<0.001), and non-home discharge (OR 1.52; p=0.014). Similar increased risk of complications was seen for patients with a mFI of 2 compared to those with a score of 0: major complications (OR 9.49; p=0.004), readmission (OR 3.73; p=0.003), postoperative transfusion (OR 4.07; p<0.001), prolonged hospital stay (OR 2.50; p<0.001), and non-home discharge (OR 2.32; p<0.001).
Higher scores on the mFI were associated with higher complication rates in patients following surgical treatment of tibial shaft fractures. The modified frailty index is a useful tool for surgeons to assess risk before operation.
本研究旨在确定构成改良虚弱指数(mFI)的因素是否与胫骨干骨折手术干预后的不良结局相关。
我们从2007年至2019年的国家数据库中识别出50岁及以上接受手术治疗的胫骨干骨折患者。为每位患者计算由糖尿病、高血压、充血性心力衰竭、依赖性功能状态和慢性阻塞性肺疾病组成的5项mFI评分。采用回归分析评估不同mFI评分与术后30天结局的关联。
本研究共纳入1159例患者(平均年龄65岁)。在多变量分析中控制混杂变量后,与mFI评分为0的患者相比,评分为1的患者发生主要并发症的风险增加(比值比[OR]5.11;p = 0.038)、次要并发症(OR 3.11;p = 0.004)、再入院(OR 2.75;p = 0.020)、术后输血(OR 2.22;p = 0.037)、住院时间延长(OR 1.88;p < 0.001)和非回家出院(OR 1.52;p = 0.014)。与评分为0的患者相比,mFI评分为2的患者也出现类似的并发症风险增加:主要并发症(OR 9.49;p = 0.004)、再入院(OR 3.73;p = 0.003)、术后输血(OR 4.07;p < 0.001)、住院时间延长(OR 2.50;p < 0.001)和非回家出院(OR 2.32;p < 0.001)。
胫骨干骨折手术治疗患者的mFI评分越高,并发症发生率越高。改良虚弱指数是外科医生术前评估风险的有用工具。