Dolapchieva S, Ichev K, Ovtscharoff W
Department of Anatomy, Medical Academy, Sofia, Bulgaria.
Acta Histochem. 1988;83(2):125-35. doi: 10.1016/S0065-1281(88)80044-8.
5'-Nucleotidase activity has been localized at the ultrastructural level in the axon-myelin-Schwann cell complex. Sciatic nerves of rabbits of pre- and postnatal development were used. Positive reaction was found on the plasma membrane, basal lamina, cytoplasm, and finger-like processes of the Schwann cells; on the intraperiod lines of the compact myelin, on the surface of myelin sheath, in the split myelin lamellae in the paranodal regions and Schmidt-Lanterman clefts, in segments of outermost and innermost lamellae, split off from the interparanodal myelin, in the mesaxons (outer and inner), in the loose myelin lamellae in the earlier stages of myelinization; on the axolemma (especially in the nodal and paranodal segments), in the periaxonal space, axoplasm. The alterations of 5'-nucleotidase distribution were associated with the developing myelin sheath.
5'-核苷酸酶活性已在轴突-髓磷脂-施万细胞复合体的超微结构水平上定位。使用了出生前和出生后发育阶段兔子的坐骨神经。在施万细胞的质膜、基膜、细胞质和指状突起上发现阳性反应；在致密髓磷脂的周期间线、髓鞘表面、结旁区域的分裂髓鞘板层和施密特-兰特尔曼切迹中、从结间髓磷脂分离的最外层和最内层板层片段中、中轴（外层和内层）、髓鞘形成早期的疏松髓鞘板层中；在轴膜（尤其是在结和结旁节段）、轴周间隙、轴质中。5'-核苷酸酶分布的改变与髓鞘的发育有关。
