Jiang H, Li X M, Zhang Y, Liu H J, Li M T, Ge H Y
Department of Pediatric Cardiology, Heart Center, the First Hospital of Tsinghua University(Beijing Huaxin Hospital), Beijing 100016, China.
Zhonghua Er Ke Za Zhi. 2017 Apr 2;55(4):267-271. doi: 10.3760/cma.j.issn.0578-1310.2017.04.007.
To explore the clinical features of atrial flutter (AFL) and evaluate the efficacy of radiofrequency catheter ablation (RFCA) for AFL in children. Data were collected and analyzed on 50 consecutive pediatric AFL patients (male 37/female 13) who underwent electrophysiology study and RFCA from February 2009 to November 2016 in a case observational study. The average age was (6.2±3.5) years and body weight was (23.7±13.5) kg. Heart structure was normal in 26 patients. Twenty-four patients had congenital heart disease (CHD) and among them 22 patients underwent repaired surgery before. Patients were followed-up for 1 month to 7 years after RFCA. Clinical features and the outcomes of RFCA in AFL patients were analyzed. The average onset age was (4.2±3.3) years. Of these patients, 84% had persistent AFL and 16% paroxysmal AFL. AFL with sick sinus syndrome (SSS) occurred in 36% patients without statistically significant difference between the groups with and without CHD (38.9%(7/18) . 61.1%(11/18), respectively, =0.239 5); 49 patients underwent RFCA except one case with atrial standstill during the procedure. The total acute success rate was 96%. The follow-up recurrence rate was 8%.No complication of the procedures was observed. The cavotricuspid isthmus-dependent AFL occurred in all patients without CHD. However, in the children with CHD after the repair surgery 10 (45%) cases were with cavotricuspid isthmus-dependent AFL, 4 (8%) with atrial scars-dependent AFL, and 8(16%) with both cavotricuspid isthmus and atrial scars-dependent AFL. RFCA was effective and safe for pediatric AFL. There is no difference on the acute success rate, the follow-up AFL recurrence rate, as well as occurrence of SSS between the groups with and without CHD. AFL patients with CHD included the cavotricuspid isthmus-dependent AFL, atrial scars-dependent AFL or both.
探讨儿童心房扑动(AFL)的临床特征,并评估射频导管消融术(RFCA)治疗儿童AFL的疗效。在一项病例观察研究中,收集并分析了2009年2月至2016年11月期间连续50例接受电生理检查和RFCA的儿科AFL患者(男37例/女13例)的数据。平均年龄为(6.2±3.5)岁,体重为(23.7±13.5)kg。26例患者心脏结构正常。24例患者患有先天性心脏病(CHD),其中22例患者之前接受过修复手术。对患者进行RFCA术后1个月至7年的随访。分析AFL患者的临床特征及RFCA的治疗结果。平均发病年龄为(4.2±3.3)岁。这些患者中,84%为持续性AFL,16%为阵发性AFL。36%的患者发生伴有病态窦房结综合征(SSS)的AFL,有CHD组和无CHD组之间无统计学差异(分别为38.9%(7/18)和61.1%(11/18),P = 0.239 5);49例患者接受了RFCA,除1例在手术过程中出现心房静止。总急性成功率为96%。随访复发率为8%。未观察到手术并发症。所有无CHD的患者均发生三尖瓣峡部依赖性AFL。然而,在接受修复手术后的CHD患儿中,10例(45%)为三尖瓣峡部依赖性AFL,4例(8%)为心房瘢痕依赖性AFL,8例(16%)为三尖瓣峡部和心房瘢痕依赖性AFL。RFCA治疗儿童AFL有效且安全。有CHD组和无CHD组在急性成功率、随访AFL复发率以及SSS发生率方面无差异。患有CHD的AFL患者包括三尖瓣峡部依赖性AFL、心房瘢痕依赖性AFL或两者皆有。