Cong Q, Wang Q, Gao S J, Zhang H W, Du M, Xie F, Dong J, Feng H, Zheng R L, Chen M, Zhu C Y, Diao W J, Song Y, Guo Q S, Li Y Y, Chen L M, Cao Y K, Sui L
Cervical Disease Center, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China.
Zhonghua Fu Chan Ke Za Zhi. 2017 Apr 25;52(4):239-243. doi: 10.3760/cma.j.issn.0529-567X.2017.04.005.
To explore the detection trend of vaginal intraepithelial neoplasia (VaIN) of lower genital tract from 2013 to 2015. A retrospective analysis was undertaken of colposcopy-directed biopsy of cervical, vaginal and vulvar intraepithelial neoplasia lesions include cervical intraepithelial neoplasia (CIN), VaIN and vulvar intraepithelial neoplasia (VIN) in Obstetrics and Gynecology Hospital of Fudan University from January 2013 to December 2015. (1) Overall data of CIN, VaIN and VIN: a total of 16 732 cases were diagnosed of lower genital intraepithelial neoplasia in 3 years, accounting for 23.20% (16 732/72 128) of total colposcopy-directed biopsy cases. Among them, CIN, VaIN and VIN accounted for 19.48% (14 053/72 128), 2.67% (1 923/72 128), 1.05% (756/72 128) of total colposcopy-directed biopsy cases of the lower genital tract, 83.99% (14 053/16 732), 11.49% (1 923/16 732), 4.52% (756/16 732) of total lower genital intraepithelial neoplasia, respectively. (2) Annual data of CIN, VaIN and VIN from 2013 to 2015. The annual proportion of CIN in all intraepithelial neoplasia of lower gential tract was basically stable, consisting of 86.02%(3 955/4 598),83.25%(4 795/5 760) and 83.20% (5 303/6 374), respectively. The annual proportion of VaIN was gradually increasing, consisting of 8.09%(372/4 598), 12.45%(717/5 760) and 13.08%(834/6 374), respectively. The annual proportion of VIN was gradually decreasing, consisting of 5.89%(271/4 598), 4.31%(248/5 760) and 3.72%(237/6 374), respectively. The increasing detection of VaIN from 2013 to 2015 might correlate with the increasing attention to inspection of the entire vaginal wall.
探讨2013年至2015年下生殖道阴道上皮内瘤变（VaIN）的检出趋势。对复旦大学附属妇产科医院2013年1月至2015年12月宫颈、阴道和外阴上皮内瘤变病变（包括宫颈上皮内瘤变（CIN）、VaIN和外阴上皮内瘤变（VIN））的阴道镜引导下活检进行回顾性分析。（1）CIN、VaIN和VIN的总体数据：3年共诊断出16732例下生殖道上皮内瘤变，占阴道镜引导下活检病例总数的23.20%（16732/72128）。其中，CIN、VaIN和VIN分别占下生殖道阴道镜引导下活检病例总数的19.48%（14053/72128）、2.67%（1923/72128）、1.05%（756/72128），分别占下生殖道上皮内瘤变总数的83.99%（14053/16732）、11.49%（1923/16732）、4.52%（756/16732）。（2）2013年至2015年CIN、VaIN和VIN的年度数据。CIN在下生殖道所有上皮内瘤变中的年度比例基本稳定，分别为86.02%（3955/4598）、83.25%（4795/5760）和83.20%（5303/6374）。VaIN的年度比例逐渐上升，分别为8.09%（372/4598）、12.45%（717/5760）和13.08%（834/6374）。VIN的年度比例逐渐下降，分别为5.89%（271/4598）、4.31%（248/5760）和3.72%（237/6374）。201
