Zhang Lei, Jiya Buren, Wang Yufei, Han Batel, Guo Zhanlin
Department of Thoracic Surgery, The Affiliated Hospital of Inner Mongolia Medical University, Huhhot 010050, China.
Zhongguo Fei Ai Za Zhi. 2017 Apr 20;20(4):248-252. doi: 10.3779/j.issn.1009-3419.2017.04.04.
Lymph node metastasis is one of the important factors affecting the tumor-node-matastasis (TNM) staging of lung cancer. In patients with surgery, 13 groups and 14 groups of lymph nodes ignored because of the deep hidden in the lung. In this paper, the positive detection rate of 13 groups and the 14 groups of lymph nodes in non-small cell lung cancer (NSCLC) and their effects on pathological stage were studied.
100 cases of NSCLC were collected from the Affiliated Hospital of Inner Mongolia Medical University as the research object, cut out the intrathoracic 2-12 group, 13, 14 lymph node metastasis rate for pathological examination, relationship factors of statistical analysis of the size of primary tumor, location, pathological type and lymph node.
100 cases of patients with intrathoracic lymph node metastasis rate was 47.0%, with the 10-12 groups lymph node, N2 lymph nodes, 13, 14 groups lymph node positive rate had significant differences (P<0.05); T stage 13, 14 groups of lymph node detection rate has statistically significant difference (P<0.05); peripheral and central NSCLC stage N1 undetected rate no statistical difference (P>0.05); various pathological types of tumors between N1 missed rate had no significant difference (P>0.05). In addition, 12 patients were found to have non-tumor-derived lobe lymph node metastasis.
CONCLUSIONS: It is necessary to detect the metastatic lymph nodes of 13,14 group and non-tumor-derived lobe in NSCLC. It is helpful to obtain accurate TNM staging and to guide postoperative treatment. .
淋巴结转移是影响肺癌肿瘤-淋巴结-转移(TNM)分期的重要因素之一。在手术患者中,第13组和第14组淋巴结因深藏于肺内而被忽视。本文研究非小细胞肺癌(NSCLC)中第13组和第14组淋巴结的阳性检出率及其对病理分期的影响。
收集内蒙古医科大学附属医院100例NSCLC患者作为研究对象,切除胸内第2 - 12组、第13、14组淋巴结进行病理检查,统计分析原发肿瘤大小、位置、病理类型与淋巴结转移的相关因素。
100例患者胸内淋巴结转移率为47.0%,与第10 - 12组淋巴结、N2淋巴结、第13、14组淋巴结阳性率有显著差异(P<0.05);T分期中第13、14组淋巴结检出率有统计学差异(P<0.05);周围型和中央型NSCLC的N1未检出率无统计学差异(P>0.05);各病理类型肿瘤之间N1漏诊率无显著差异(P>0.05)。此外,发现12例患者有非肿瘤来源叶的淋巴结转移。
NSCLC中检测第13、14组及非肿瘤来源叶的转移淋巴结很有必要。有助于获得准确的TNM分期并指导术后治疗。