Kraicer J, Lussier B, Kotanen S, Moor B C
Department of Physiology, University of Western Ontario, London, Canada.
Can J Physiol Pharmacol. 1988 Apr;66(4):318-20. doi: 10.1139/y88-054.
Neuropeptide Y in concentrations from 10(-8) to 10(-6) M inhibits the release of alpha-MSH from the frog (Rana pipiens) pituitary in a reversible, sustained, and concentration-related manner. However, it does not inhibit the release of alpha-MSH from the rat pars intermedia. Thus, while neuropeptide Y may play a role in the control of alpha-MSH release in amphibia, it appears not to be a regulatory peptide for the mammalian pars intermedia.
浓度为10⁻⁸至10⁻⁶M的神经肽Y以可逆、持续且与浓度相关的方式抑制青蛙(豹蛙)垂体中α-促黑素(α-MSH)的释放。然而,它并不抑制大鼠中间部中α-MSH的释放。因此,虽然神经肽Y可能在两栖动物α-MSH释放的控制中发挥作用,但它似乎不是哺乳动物中间部的调节肽。