Soares Ana Luiza Gonçalves, Gonçalves Helen, Matijasevich Alicia, Sequeira Maija, Smith George Davey, Menezes Ana M B, Assunção Maria Cecília, Wehrmeister Fernando C, Fraser Abigail, Howe Laura D
Am J Epidemiol. 2017 May 15;185(10):898-906. doi: 10.1093/aje/kwx007.
The aim of this study was to explore the association between parental separation during childhood (up to 18 years of age) and cardiometabolic risk factors (body mass index, fat mass index, blood pressure, physical activity, smoking, and alcohol consumption) in late adolescence using a cross-cohort comparison and to explore whether associations differ according to the age at which the parental separation occurred and the presence or absence of parental conflict prior to separation. Data from the Avon Longitudinal Study of Parents and Children (ALSPAC, United Kingdom) (1991-2011) and the 1993 Pelotas Birth Cohort (Brazil) (1993-2011) were used. The associations of parental separation with children's cardiometabolic risk factors were largely null. Higher odds of daily smoking were observed in both cohorts for those adolescents whose parents separated (for ALSPAC, odds ratio = 1.46; for Pelotas Birth Cohort, odds ratio = 1.98). Some additional associations were observed in the Pelotas Birth Cohort but were generally in the opposite direction to our a priori hypothesis: Parental separation was associated with lower blood pressure and fat mass index, and with more physical activity. No consistent differences were observed when analyses were stratified by child's age at parental separation or parental conflict.
本研究旨在通过跨队列比较,探讨童年时期(至18岁)父母离异与青少年晚期心脏代谢危险因素(体重指数、脂肪量指数、血压、身体活动、吸烟和饮酒)之间的关联,并探讨这些关联是否因父母离异发生的年龄以及离异前父母冲突的有无而有所不同。我们使用了英国埃文父母与儿童纵向研究(ALSPAC,1991 - 2011年)和巴西1993年佩洛塔斯出生队列(1993 - 2011年)的数据。父母离异与儿童心脏代谢危险因素之间的关联大多不显著。在两个队列中,父母离异的青少年每日吸烟的几率更高(对于ALSPAC,优势比 = 1.46;对于佩洛塔斯出生队列,优势比 = 1.98)。在佩洛塔斯出生队列中还观察到了一些其他关联,但总体上与我们的先验假设方向相反:父母离异与较低的血压和脂肪量指数以及更多的身体活动有关。当按父母离异时孩子的年龄或父母冲突进行分层分析时,未观察到一致的差异。